spoVT
168
transcription activator and repressor of [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]-dependent genes
locus
BSU_00560
Molecular weight
19.60 kDa
pI
4.68
function
regulation of forespore gene expression
product
transcriptional regulator
essential
no
synonyms
spoVT, yabL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5845 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
64,099 64,635
The protein
[wiki|Domains]
[wiki|SpoVT-AbrB domain] (aa 5-51) (according to UniProt)
Structure
[PDB|2W1R] (full-length), [PDB|2W1T] (C-terminal domain) [PDB|2RO5] (recognition domain)
[AF|P37554]
Paralogous protein(s)
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]
[protein|5872812AB61E92E2944E926915EB7FEE71BFA6D5|abh], (only the N-terminal domains (aa 1 through 50) are conserved between SpoVT and the two paralogues)
[wiki|Localization]
Cytoplasm (Homogeneous) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
description
[Pubmed|8755877]
regulation
expressed in the forespore ([protein|search|SigG]) [Pubmed|8755877]
sigma factors
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|15699190], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|15699190,8755877], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
genes
[gene|C595D32D98723E93AF26B5C864FD61AF4739E069|fin]-[gene|AD1F39823ABCE2A222259B879513752942C59590|mfd]-[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
description
[pubmed|22383849]
expression
expression is heterogeneous [pubmed|35171018]
Biological materials
Mutant
BKE00560 ([gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTC
BKK00560 ([gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTC
References
Reviews
Original Publications
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Time of last update: 2024-12-21 08:24:37
Author of last update: Jstuelk