yabD
168
putative metal-dependent hydrolase
locus
BSU_00390
Molecular weight
29.08 kDa
pI
4.81
function
unknown
product
putative metal-dependent hydrolase
essential
no
synonyms
yabD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0084 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
47,706 48,473
The protein
Protein family
[wiki|Metallo-dependent hydrolases superfamily] (according to UniProt)
Structure
[PDB|2GZX] (from Staphylococcus aureus, 64% identity)
[AF|P37545]
[wiki|Localization]
cytoplasm (according to UniProt)
Expression and Regulation
Operons
genes
[gene|DCBDD135F295B04FE7C7EB92E94638701CB320DD|metS]-[gene|00798BB5A769C464CC5FDDF7D9E41D30B473B9A8|yabD]
description
[Pubmed|22383849] null
regulation
repressed under conditions that trigger sporulation ([wiki|Spo0A]) [Pubmed|14651647]
regulatory mechanism
[protein|2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A]: repression, [pubmed|14651647], in [regulon|protein:2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A regulon]
additional information
term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of [gene|DCBDD135F295B04FE7C7EB92E94638701CB320DD|metS] [Pubmed|27120414]
Biological materials
Mutant
MGNA-B904 (yabD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1903 NBRP B. subtilis, Japan]
BKE00390 ([gene|00798BB5A769C464CC5FDDF7D9E41D30B473B9A8|yabD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE00390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAGTGAAAAACTCCTTT, downstream forward: _UP4_TGACAAAAAACGCTAGCGGG
BKK00390 ([gene|00798BB5A769C464CC5FDDF7D9E41D30B473B9A8|yabD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK00390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAGTGAAAAACTCCTTT, downstream forward: _UP4_TGACAAAAAACGCTAGCGGG
References
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Time of last update: 2025-04-11 07:26:28
Author of last update: Jstuelk