Category: Genetic competence

[category|SW.4|4. Lifestyles]

[category|SW.4.1|4.1. Exponential and early post-exponential lifestyles]

[category|SW.4.1.3|4.1.3. Genetic competence]

Name	Function
[gene\|49E8BFEC1CAB77DD91E0ED0791EBD480E4871239\|addA]	DNA repair/ recombination
[gene\|55A1EF8A10CB398CCD3FDD06D9483FE0DCE31C64\|addB]	DNA repair/ recombination
[gene\|A01637E1BFABA20A2923BA85A25CCD8A0D665F78\|bdbC]	oxidative folding of proteins
[gene\|CED818CEF5B573A40F382157375E60C0B331F098\|bdbD]	oxidative folding of proteins
[gene\|0B1F5A160ADFF3EA904122A7E43E13C5828B31BE\|coiA]	genetic competence
[gene\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA]	regulation of genetic competence and quorum sensing
[gene\|57FDE2ABB5E9773717C23D727FD6CDA5D8CC3E36\|comC]	genetic competence
[gene\|788725411B2E741103603373E43441FD036E1BA0\|comEA]	genetic competence
[gene\|954359717E15DFC106A9D8111C6637E46B16F8C9\|comEB]	nucleotide scavenging
[gene\|363C6FE07C5E56FDE6BEC6ACFBA1A5535F0F64AC\|comEC]	genetic competence
[gene\|9840EA950FD7F4D18FDD0AB9AC65491E9F8BCC1C\|comER]	control of biofilm formation and sporulation via the phosphorelay
[gene\|45F27C0789199626BA90D2C69E8F13525C911478\|comFA]	genetic competence
[gene\|D290247A43280532947B707F3AF388D7A7F404D3\|comFB]	compentence
[gene\|04D9D70C0BCFDCBD00B5156908C348135080A9C2\|comFC]	nucleotide scavenging
[gene\|41DFEF8A6BC7E34A6681C26D92F2B08DC120A957\|comGA]	genetic competence
[gene\|EA1C841FC77A1994A85E2E0C0A554482C3EC9323\|comGB]	genetic competence, DNA uptake
[gene\|19D76B80386F825109C5FB4A34881D5D20F366DB\|comGC]	genetic competence
[gene\|D323AEF5AFB4FD2A074ABAB76A39BE26A4C6436F\|comGD]	genetic competence, DNA uptake
[gene\|FF4DB7FDCEB440064E11E65CB0DBFB93FC785CF0\|comGE]	genetic competence, DNA uptake
[gene\|DD266DC0D78B5C5E82EED7CC7F55D0CF8FB4BF7A\|comGF]	genetic competence, DNA uptake
[gene\|89442BFDFBFF264D0C7F12DEA6F8130C55D1F3F8\|comGG]	genetic competence, DNA uptake
[gene\|08CFA2C72931A75532D4289BC1D18A826DE9F9CA\|comK]	regulation of [wiki\|genetic competence] and DNA uptake
[gene\|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7\|comN]	regulation of competence and DNA uptake
[gene\|5A00E233F0B5A0DAB18D2ECC55527F1911987F86\|comP]	regulation of genetic competence and quorum sensing
[gene\|FDACEF9DDC3BEA4EB013AE67BC47ADA532F00205\|comQ]	regulation of quorum sensing
[gene\|4D76F07D6124D56C7CEBBDAB9E84B2718BF1E7FC\|comS]	control of ComK degradation
[gene\|60D6EB02923D9ADE88F61A8CBBD882BA8BDD457E\|comX]	[category\|SW.3.4.8\|Quorum sensing]
[gene\|8914DE1312FD3C28E7D451A034814D92D1312B10\|comZ]	compentence
[gene\|FC53216F600994C862F0C0D017C3FA28EB75DCB6\|dprA]	[category\|SW.3.1.5\|DNA repair/ recombination]
[gene\|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB\|hag]	[wiki\|motility and chemotaxis]
[gene\|65E2F7197D46F5C884CC96018EE4F3EEE94FFA18\|kre]	control of [protein\|search\|ComK ]accumulation and of bistable competence gene expression
[gene\|331993A875907C10C77105FD8DDD86D4412CE405\|mecA]	control of [protein\|08CFA2C72931A75532D4289BC1D18A826DE9F9CA\|comK] degradation, regulation of competence
[gene\|4DAB7847EA3848A34432C80124464543FA3DCA0F\|med]	regulation of competence
[gene\|FE56753D061344B0F10A6523F49C5C7356AA40B6\|motB]	[category\|SW.4.1.1\|Motility and chemotaxis]
[gene\|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23\|nin]	genetic transformation, DNA uptake
[gene\|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75\|nucA]	genetic transformation, DNA uptake
[gene\|302DFA46D73E18C4663468ED6033C55056744475\|oppA]	initiation of [wiki\|sporulation], competence development
[gene\|B0A3C7B253FB1DA1D4BC9D1D564905ECE8A65BC1\|oppB]	initiation of [wiki\|sporulation], competence development
[gene\|DDBCE73B6AF39E5D669475479186C93F287DA9FC\|oppC]	initiation of [wiki\|sporulation], competence development
[gene\|05752B9C4EA7ACD579D65D028B7DF1861F3840CB\|oppD]	initiation of [wiki\|sporulation], competence development
[gene\|38AD697B6C9967B8BD7496E31264A21F6D0A9DEE\|oppF]	initiation of sporulation, competence development
[gene\|C0B7845F55A16300EB37F026C817AEC4F3BA3B6F\|phrC]	control of ComA activity
[gene\|AEBEDF43C56A9A54716D781D062067B69818FAF4\|phrF]	control of ComA activity
[gene\|886C1BAE024A9D1A6C7C4F16E5251D5427B8D41E\|phrK]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|64C6D783FF3F41C81B216F798A1DC8071345B1ED\|pnpA]	DNA repair, competence development, RNA degradation
[gene\|2BD11D71AA6D9EFAD8A209C8813CC8B059180C84\|radC]	DNA repair
[gene\|242632B27E0E3AB15777E9FBA3FC746D00CE97F9\|rapC]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|4670F7C4CB9084A5BA478CAE238FA0F8C39F3A7E\|rapD]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA]-dependent gene expression
[gene\|1F860F4E66A3D503D5A97F17D4AB0504BEFE7F9D\|rapF]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|C8BF3815578293542D14811C60F4CA78AACF73EB\|rapK]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|A44D4677FB70BE8F554BF1001A500F817C7DA95F\|recA]	DNA repair/ recombination
[gene\|1508770D5BCA5739D13E3ABD11CC5C103C07FF25\|rok]	control of genome organization, silencing of horizontally acquired genes
[gene\|ED825D5B3290BA8F9C92477B1FCC433ADB3C8449\|sbcC]	DNA inter-strand cross-link repair
[gene\|4D89BFFB1073407A7A1762AFD18B49F3414D6787\|sbcD]	unknown
[gene\|1CDF658441061EA476E27C2E60DEE45C4F45AC15\|ssbB]	required for efficient genetic transformation
[gene\|96136B1EDFAA1A34ED012CB5BA1DDFB8A95FB4A1\|yhfW]	unknown
[gene\|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036\|yhxC]	unknown
[gene\|121A9543F5BC1CBE77D85A34099DE09F8AC63E9F\|yidC2]	membrane insertion of proteins and protein secretion
[gene\|EB12C6B4F36B57BF0C59CE048CBAE18734C78D35\|yvcJ]	required for the expression of late competence genes

additional information

The wild type strain NCIB3610 is only poorly competent because the small protein ComI encoded on the endogenous plasmid pBS32 inhibits the competence DNA uptake machinery. [pubmed|23836866]

important original publications

23836866,24012503

important reviews

15083159,19228200,10607621,9224890,1943994,19995980,12576575,23046409,22146301,23551850,23572583,23693123,23669271,25547840,31950915

Page visits: 942

Time of last update: 2025-03-11 19:03:36

Author of last update: Jstuelk

Name	Function
[gene\|49E8BFEC1CAB77DD91E0ED0791EBD480E4871239\|addA]	DNA repair/ recombination
[gene\|55A1EF8A10CB398CCD3FDD06D9483FE0DCE31C64\|addB]	DNA repair/ recombination
[gene\|A01637E1BFABA20A2923BA85A25CCD8A0D665F78\|bdbC]	oxidative folding of proteins
[gene\|CED818CEF5B573A40F382157375E60C0B331F098\|bdbD]	oxidative folding of proteins
[gene\|0B1F5A160ADFF3EA904122A7E43E13C5828B31BE\|coiA]	genetic competence
[gene\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA]	regulation of genetic competence and quorum sensing
[gene\|57FDE2ABB5E9773717C23D727FD6CDA5D8CC3E36\|comC]	genetic competence
[gene\|788725411B2E741103603373E43441FD036E1BA0\|comEA]	genetic competence
[gene\|954359717E15DFC106A9D8111C6637E46B16F8C9\|comEB]	nucleotide scavenging
[gene\|363C6FE07C5E56FDE6BEC6ACFBA1A5535F0F64AC\|comEC]	genetic competence
[gene\|9840EA950FD7F4D18FDD0AB9AC65491E9F8BCC1C\|comER]	control of biofilm formation and sporulation via the phosphorelay
[gene\|45F27C0789199626BA90D2C69E8F13525C911478\|comFA]	genetic competence
[gene\|D290247A43280532947B707F3AF388D7A7F404D3\|comFB]	compentence
[gene\|04D9D70C0BCFDCBD00B5156908C348135080A9C2\|comFC]	nucleotide scavenging
[gene\|41DFEF8A6BC7E34A6681C26D92F2B08DC120A957\|comGA]	genetic competence
[gene\|EA1C841FC77A1994A85E2E0C0A554482C3EC9323\|comGB]	genetic competence, DNA uptake
[gene\|19D76B80386F825109C5FB4A34881D5D20F366DB\|comGC]	genetic competence
[gene\|D323AEF5AFB4FD2A074ABAB76A39BE26A4C6436F\|comGD]	genetic competence, DNA uptake
[gene\|FF4DB7FDCEB440064E11E65CB0DBFB93FC785CF0\|comGE]	genetic competence, DNA uptake
[gene\|DD266DC0D78B5C5E82EED7CC7F55D0CF8FB4BF7A\|comGF]	genetic competence, DNA uptake
[gene\|89442BFDFBFF264D0C7F12DEA6F8130C55D1F3F8\|comGG]	genetic competence, DNA uptake
[gene\|08CFA2C72931A75532D4289BC1D18A826DE9F9CA\|comK]	regulation of [wiki\|genetic competence] and DNA uptake
[gene\|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7\|comN]	regulation of competence and DNA uptake
[gene\|5A00E233F0B5A0DAB18D2ECC55527F1911987F86\|comP]	regulation of genetic competence and quorum sensing
[gene\|FDACEF9DDC3BEA4EB013AE67BC47ADA532F00205\|comQ]	regulation of quorum sensing
[gene\|4D76F07D6124D56C7CEBBDAB9E84B2718BF1E7FC\|comS]	control of ComK degradation
[gene\|60D6EB02923D9ADE88F61A8CBBD882BA8BDD457E\|comX]	[category\|SW.3.4.8\|Quorum sensing]
[gene\|8914DE1312FD3C28E7D451A034814D92D1312B10\|comZ]	compentence
[gene\|FC53216F600994C862F0C0D017C3FA28EB75DCB6\|dprA]	[category\|SW.3.1.5\|DNA repair/ recombination]
[gene\|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB\|hag]	[wiki\|motility and chemotaxis]
[gene\|65E2F7197D46F5C884CC96018EE4F3EEE94FFA18\|kre]	control of [protein\|search\|ComK ]accumulation and of bistable competence gene expression
[gene\|331993A875907C10C77105FD8DDD86D4412CE405\|mecA]	control of [protein\|08CFA2C72931A75532D4289BC1D18A826DE9F9CA\|comK] degradation, regulation of competence
[gene\|4DAB7847EA3848A34432C80124464543FA3DCA0F\|med]	regulation of competence
[gene\|FE56753D061344B0F10A6523F49C5C7356AA40B6\|motB]	[category\|SW.4.1.1\|Motility and chemotaxis]
[gene\|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23\|nin]	genetic transformation, DNA uptake
[gene\|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75\|nucA]	genetic transformation, DNA uptake
[gene\|302DFA46D73E18C4663468ED6033C55056744475\|oppA]	initiation of [wiki\|sporulation], competence development
[gene\|B0A3C7B253FB1DA1D4BC9D1D564905ECE8A65BC1\|oppB]	initiation of [wiki\|sporulation], competence development
[gene\|DDBCE73B6AF39E5D669475479186C93F287DA9FC\|oppC]	initiation of [wiki\|sporulation], competence development
[gene\|05752B9C4EA7ACD579D65D028B7DF1861F3840CB\|oppD]	initiation of [wiki\|sporulation], competence development
[gene\|38AD697B6C9967B8BD7496E31264A21F6D0A9DEE\|oppF]	initiation of sporulation, competence development
[gene\|C0B7845F55A16300EB37F026C817AEC4F3BA3B6F\|phrC]	control of ComA activity
[gene\|AEBEDF43C56A9A54716D781D062067B69818FAF4\|phrF]	control of ComA activity
[gene\|886C1BAE024A9D1A6C7C4F16E5251D5427B8D41E\|phrK]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|64C6D783FF3F41C81B216F798A1DC8071345B1ED\|pnpA]	DNA repair, competence development, RNA degradation
[gene\|2BD11D71AA6D9EFAD8A209C8813CC8B059180C84\|radC]	DNA repair
[gene\|242632B27E0E3AB15777E9FBA3FC746D00CE97F9\|rapC]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|4670F7C4CB9084A5BA478CAE238FA0F8C39F3A7E\|rapD]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA]-dependent gene expression
[gene\|1F860F4E66A3D503D5A97F17D4AB0504BEFE7F9D\|rapF]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|C8BF3815578293542D14811C60F4CA78AACF73EB\|rapK]	control of [protein\|7832489F11F606BCF637EC23BAAB41AD10237EBB\|comA] activity
[gene\|A44D4677FB70BE8F554BF1001A500F817C7DA95F\|recA]	DNA repair/ recombination
[gene\|1508770D5BCA5739D13E3ABD11CC5C103C07FF25\|rok]	control of genome organization, silencing of horizontally acquired genes
[gene\|ED825D5B3290BA8F9C92477B1FCC433ADB3C8449\|sbcC]	DNA inter-strand cross-link repair
[gene\|4D89BFFB1073407A7A1762AFD18B49F3414D6787\|sbcD]	unknown
[gene\|1CDF658441061EA476E27C2E60DEE45C4F45AC15\|ssbB]	required for efficient genetic transformation
[gene\|96136B1EDFAA1A34ED012CB5BA1DDFB8A95FB4A1\|yhfW]	unknown
[gene\|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036\|yhxC]	unknown
[gene\|121A9543F5BC1CBE77D85A34099DE09F8AC63E9F\|yidC2]	membrane insertion of proteins and protein secretion
[gene\|EB12C6B4F36B57BF0C59CE048CBAE18734C78D35\|yvcJ]	required for the expression of late competence genes