Category: Metabolism of signalling nucleotides

[category|SW.2|2. Metabolism]

[category|SW.2.5|2.5. Nucleotide metabolism]

[category|SW.2.5.3|2.5.3. Metabolism of signalling nucleotides]

Name	Function
[gene\|AFE2A9998219162FE32E95628B3CA9071099B61A\|cdaA]	synthesis of [metabolite\|c-di-AMP]
[gene\|FB23F2AB0E2A82658009D115E5876E7AF1BDE5FD\|cdaR]	regulation of c-di-AMP synthesis
[gene\|92EF98B872C1AD729B0BFAD46D3FA572E9C2AA32\|cdaS]	synthesis of [metabolite\|c-di-AMP]
[gene\|90AFF93D6E7BC993B2773C12EE400C80A87A4831\|darB]	control of [protein\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel] activity, trigger of the stringent response under conditions of potassium starvation
[gene\|C43AE224400421CCDA7022C915ECC7525E30EB1D\|dgcK]	synthesis of c-di-GMP
[gene\|4C577B2CEDD9CD2CBFAF036EF36C9EFAF16F923F\|dgcP]	synthesis of c-di-GMP
[gene\|A2E6852A5739B3C04405B98AFFC301A98E1ADCD0\|dgcW]	synthesis of c-di-GMP
[gene\|2B091CCEE9E34D659771E39B1FC9050A145048AB\|disA]	control of [wiki\|sporulation] initiation, synthesis of [metabolite\|c-di-AMP]
[gene\|9B624751E8BD3EA616B4B50633A558F4CE032E2C\|gdpP]	control of sporulation initiation, cell wall homeostasis
[gene\|F022ACB2CBB8DA46B392CE1D26474093645F26DA\|glmM]	cell wall synthesis, control of c-di-AMP synthesis
[gene\|24CC89DE55B3C19F80B11D106B9FD241174AE3E4\|lysS]	translation
[gene\|0C40455EB53D25363FC3EB0E84502A76520F5F91\|nahA]	initiation of RNA degradation
[gene\|02628F274952F9AEEE9F2224B771A4CE4AAD1C8D\|pdeH]	degradation of c-di-GMP
[gene\|8D0885839CD60C05FB806BBF08AFA05225E83B12\|pgpH]	control of c-di-AMP homeostasis
[gene\|151F226370D225776F3FE7EA4901485095F1AC45\|radA]	homologous recombination, control of c-di-AMP formation, co-ordination of responses to replicative stress and genetic recombination
[gene\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel]	synthesis and degradation of (p)[metabolite\|ppGpp], triggering the stringent response regulon
[gene\|1107A963C253FBEE8716507BD0EC0E7CD5642B12\|sasA]	ppGpp synthesis independent from stringent response
[gene\|81BCF5C08EC1A580F5E05884BA830130FC7E46E9\|sasB]	ppGpp synthesis independent from stringent response
[gene\|188742B9A0C95344D32A4C23B9C971660572CF7D\|ycnB]	secretion of cyclic di-AMP
[gene\|B791B0603042603CB5B5E03CA129B20D02BC02BC\|yfkN]	degradation of c-di-AMP
[gene\|93159DC7D5C42CFA54F66F232D73F38957243AB7\|yhcA]	secretion of cyclic di-AMP
[gene\|247C47AC70A0EA53E625871D9BC463A06E6B05FB\|yqeK]	degradation of Ap₄A, degradation of toxic side-products of [protein\|AA4BB1F5B58371D536A6BBA86F6ECB5E5BFB12A8\|nadD] activity

Related category

[category|search|Targets of second messengers]

important original publications

24141192,23192352,23893111,25605304,31138629

important reviews

21255104,16045609,19756011,19287449,18714086,23023210,23812326,25636134,25869574,26773214,30224435,30980074,32095817,32472931,32603625,32881708,34416118,37022175,37954098,39216180,38262803

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Time of last update: 2024-10-06 14:45:40

Author of last update: Jstuelk

Name	Function
[gene\|AFE2A9998219162FE32E95628B3CA9071099B61A\|cdaA]	synthesis of [metabolite\|c-di-AMP]
[gene\|FB23F2AB0E2A82658009D115E5876E7AF1BDE5FD\|cdaR]	regulation of c-di-AMP synthesis
[gene\|92EF98B872C1AD729B0BFAD46D3FA572E9C2AA32\|cdaS]	synthesis of [metabolite\|c-di-AMP]
[gene\|90AFF93D6E7BC993B2773C12EE400C80A87A4831\|darB]	control of [protein\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel] activity, trigger of the stringent response under conditions of potassium starvation
[gene\|C43AE224400421CCDA7022C915ECC7525E30EB1D\|dgcK]	synthesis of c-di-GMP
[gene\|4C577B2CEDD9CD2CBFAF036EF36C9EFAF16F923F\|dgcP]	synthesis of c-di-GMP
[gene\|A2E6852A5739B3C04405B98AFFC301A98E1ADCD0\|dgcW]	synthesis of c-di-GMP
[gene\|2B091CCEE9E34D659771E39B1FC9050A145048AB\|disA]	control of [wiki\|sporulation] initiation, synthesis of [metabolite\|c-di-AMP]
[gene\|9B624751E8BD3EA616B4B50633A558F4CE032E2C\|gdpP]	control of sporulation initiation, cell wall homeostasis
[gene\|F022ACB2CBB8DA46B392CE1D26474093645F26DA\|glmM]	cell wall synthesis, control of c-di-AMP synthesis
[gene\|24CC89DE55B3C19F80B11D106B9FD241174AE3E4\|lysS]	translation
[gene\|0C40455EB53D25363FC3EB0E84502A76520F5F91\|nahA]	initiation of RNA degradation
[gene\|02628F274952F9AEEE9F2224B771A4CE4AAD1C8D\|pdeH]	degradation of c-di-GMP
[gene\|8D0885839CD60C05FB806BBF08AFA05225E83B12\|pgpH]	control of c-di-AMP homeostasis
[gene\|151F226370D225776F3FE7EA4901485095F1AC45\|radA]	homologous recombination, control of c-di-AMP formation, co-ordination of responses to replicative stress and genetic recombination
[gene\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel]	synthesis and degradation of (p)[metabolite\|ppGpp], triggering the stringent response regulon
[gene\|1107A963C253FBEE8716507BD0EC0E7CD5642B12\|sasA]	ppGpp synthesis independent from stringent response
[gene\|81BCF5C08EC1A580F5E05884BA830130FC7E46E9\|sasB]	ppGpp synthesis independent from stringent response
[gene\|188742B9A0C95344D32A4C23B9C971660572CF7D\|ycnB]	secretion of cyclic di-AMP
[gene\|B791B0603042603CB5B5E03CA129B20D02BC02BC\|yfkN]	degradation of c-di-AMP
[gene\|93159DC7D5C42CFA54F66F232D73F38957243AB7\|yhcA]	secretion of cyclic di-AMP
[gene\|247C47AC70A0EA53E625871D9BC463A06E6B05FB\|yqeK]	degradation of Ap₄A, degradation of toxic side-products of [protein\|AA4BB1F5B58371D536A6BBA86F6ECB5E5BFB12A8\|nadD] activity