Category: Nucleotide metabolism

[category|SW.2|2. Metabolism]

[category|SW.2.5|2.5. Nucleotide metabolism]

[category|SW.2.5.1|2.5.1. Utilization of nucleotides]

Name	Function
[gene\|A85EB6E97AC9B2CA46BA6EF315BDA72A035DD3E7\|adeC]	utilization of adenine as nitrogen source,purine salvage and interconversion
[gene\|E9C4C569F18B3335DA9C7FB5B17C87D661E62669\|deoR]	regulation of deoxyribonucleotide utilization
[gene\|81CD1F97E887549F7FB742FCEF38B86B84383F5D\|dra]	utilization of nucleotides as carbon source
[gene\|9D07E43BF1FFB13CCEAC2B7AAA4EBDFB1079DD74\|drm]	utilization of deoxyribose
[gene\|5A3CEDBF81E3263FDB10AC9245D28498C9332D14\|nucB]	DNA degradation after mother cell lysis
[gene\|4F718681A7AD0C86B2551248570F493AC0B2E7E9\|nupC]	pyrimidine uptake
[gene\|D2EB7BBAC8817912DAC4E215879F5A4E2C47ECAF\|pdp]	pyrimidine interconversion
[gene\|C9370B221117B89A1134B413748D39505C2E1DA8\|pucA]	purine utilization
[gene\|99428BD0B1A8E91F4B028ACF8AB51B235DDB4F11\|pucB]	purine utilization
[gene\|D0F00ACF5AAD9E9418033F5B47527C4D50007F18\|pucC]	purine utilization
[gene\|B65E4B340961332ED0ACC7FD957351256F708F60\|pucD]	purine utilization
[gene\|6855CC156FCB4C4A16AFD6ADE18F3FFC82B61843\|pucE]	purine utilization
[gene\|C314CE9D194E8894430368C5F69C0778D45A651C\|pucF]	purine utilization
[gene\|4BC4B3E0AB4779D1DD5EDF591361FC1094AF661F\|pucG]	purine utilization
[gene\|8C53FEBB2BCCE45A686119B7ECE4C266D2C0822A\|pucH]	purine utilization
[gene\|5681A5F186AD4B8C81B78FD9DDAE2C0624BE7CAF\|pucI]	purine utilization
[gene\|53950BFDC128DE46F3F43BDB9D0FDB3D645152DF\|pucJ]	purine utilization
[gene\|3162EF36F4441A1E4EBBFDAD19F6768D8EF21B29\|pucK]	purine utilization
[gene\|2E7DEC53A130247E66225E87950D702E462C324F\|pucL]	purine utilization
[gene\|A2F93FFE225DFDBCBB3EA079BEF84C79465F0E5C\|pucM]	purine utilization
[gene\|52C1601482C26400A524E880334BB801F832D6ED\|pucR]	regulation of purine utilization

[category|SW.2.5.2|2.5.2. Biosynthesis/ acquisition of nucleotides]

[category|SW.2.5.2.1|2.5.2.1. Biosynthesis/ acquisition of purine nucleotides]

Name	Function
[gene\|DD3A39A84E53A9B2ACBDD89DFAE3560E45C08DC1\|adk]	ADP formation
[gene\|1BC994DE60A7BB35DEDD7154581A396D29AA94A7\|gmk]	GTP biosynthesis
[gene\|AC67305E4C165CC1D785E49B7CD8335346134376\|guaA]	biosynthesis of GMP
[gene\|AB3D18228DB6819B0C81BC7A8BB3408A4F75DC0C\|guaB]	biosynthesis of GMP
[gene\|C333F405F597FF260FFA0EC616B8CF6BF454815B\|nupG]	purine uptake
[gene\|19BA45BD691BBA4B23C4741C63DB729AA5D30FDA\|nupN]	uptake of [metabolite\|guanosine]
[gene\|71546D1508EF17A208332E162CAE2C299987A569\|nupO]	uptake of [metabolite\|guanosine]
[gene\|0BB235F189D30C9BE798560C31DA59FF0112CFD9\|nupP]	uptake of [metabolite\|guanosine]
[gene\|7A80910F4E62BA15DE93FFC70E1908FB5CB9542D\|nupQ]	uptake of [metabolite\|guanosine]
[gene\|41DDD3AAFE89D0F52AB5ABD08CEE30A1767FFD7A\|pbuG]	hypoxanthine and guanine uptake
[gene\|7D56F85FBD3AAC66607DD7465592EEAE09D61C98\|pbuX]	xanthine uptake
[gene\|37664AAEBFFDE1F7D17EA7C032805EA051FBE6AF\|prs]	phosphoribosylpyrophosphate synthesis (biosynthesis of histidine)
[gene\|AB4B8B7325A1BF444D841EF1BBBCEC2D506AE600\|purA]	purine biosynthesis
[gene\|29FF54E2B9F4A11811F5E15885A4C02A259C7B35\|purB]	purine biosynthesis
[gene\|447D12E940C7F45B6C5015844F9DED9D513CD6E5\|purC]	purine biosynthesis
[gene\|9BBA22B09C6DD6C36E043D44B0F54BD0FFA5BA0E\|purD]	purine biosynthesis
[gene\|1A9F7847AA1EB2A264842B44CD1B1A21F0AF6E57\|purE]	purine biosynthesis
[gene\|4AA5AF9C7CE8D0A9FD3A47650ECF130BCBEE1952\|purF]	purine biosynthesis
[gene\|54CE8EB2F5D1F9AEAA497E1F60248C9B2250B01E\|purH]	purine biosynthesis
[gene\|0DA73E4D1935F6A91BE251EF2704A11DE5D81174\|purK]	purine biosynthesis
[gene\|D34203FAA84C19B34B3CB5F00AC2E2663FFA344D\|purL]	purine biosynthesis
[gene\|AD0DE9457D70DF02FA0F58867B24ABF236FAF65A\|purM]	purine biosynthesis
[gene\|7B30F27D6C459437967A64467E52961F4A9E0F2C\|purN]	purine biosynthesis
[gene\|DEE856E83E790EB57F103F7A9156408AF090995D\|purQ]	purine biosynthesis
[gene\|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C\|purR]	regulation of purine biosynthesis
[gene\|CCD4DA969086181CFA33D6D241F2CAAE02E0C758\|purS]	purine biosynthesis
[gene\|C00E34EF63B5EAE33CAD5E469893C0A5112B9F35\|purT]	purine biosynthesis
[gene\|9A399CAA672C3DF90531A7A7168916DE86EFA365\|ykkE]	purine nucleotide synthesis

[category|SW.2.5.2.2|2.5.2.2. Biosynthesis/ acquisition of purine nucleotides/ based on similarity]

Name	Function
[gene\|62AC66725C55B9E5FBBEB4EC43A88F7081B74D5C\|pbuO]	unknown

[category|SW.2.5.2.3|2.5.2.3. Purine salvage and interconversion]

Name	Function
[gene\|38DF74800FC5D54183C58B0EB82BD9A3EB93EE33\|apt]	purine salvage and interconversion
[gene\|D749382783437F40AE1C66755F57D44E3FCA193F\|dck]	purine salvage and interconversion
[gene\|3075327DBE55C4F628171AEE248CAED5870693FA\|deoD]	purine salvage and interconversion
[gene\|0DA340B3D23B63C6BD284BF86409558A31B12B53\|dgk]	purine salvage and interconversion
[gene\|350A0C0D0ADB2A8E8DA9900E75A0D9914F18C665\|guaC]	purine salvage and interconversion
[gene\|AEEC5CAC20D3A182074332087FD3CDCCF05F28CC\|guaD]	deamination of guanine to xanthine, purine salvage and interconversion
[gene\|B7BFC170EEC88DEC6CF932F80805D3F2C0BD3738\|hprT]	purine salvage and interconversion, control of [gene\|4E7B9426CED372AA8A321A147116A3A589FBF20C\|ftsH] expression
[gene\|BC6FA7677AAE6BA24530D125007A18056D75DADF\|pupG]	purine salvage and interconversion
[gene\|02C84C9A8C0008CC253CBF13584A4B5B2D2B510C\|xpt]	purine salvage and interconversion

[category|SW.2.5.2.4|2.5.2.4. Biosynthesis/ acquisition of pyrimidine nucleotides]

Name	Function
[gene\|1ADB6E2C8DC82A242CFEFAD22443D14226F1BA60\|cmk]	synthesis of CTP and dCTP
[gene\|37664AAEBFFDE1F7D17EA7C032805EA051FBE6AF\|prs]	phosphoribosylpyrophosphate synthesis (biosynthesis of histidine)
[gene\|E7741ED6F15044900BDC5F0584246469D2D4D586\|pyrAA]	pyrimidine biosynthesis
[gene\|D57DC8A53E52BC4A2EA894E3C9FD983592882918\|pyrAB]	pyrimidine biosynthesis
[gene\|B83462A50FDDD20FE9BD4681824E30AAD10F506B\|pyrB]	pyrimidine biosynthesis
[gene\|CA16FD3507DCCADB1E01DF25B42C3405C9205B05\|pyrC]	pyrimidine biosynthesis
[gene\|E533BEF28579CD04B24E2C728737269E35224450\|pyrD]	pyrimidine biosynthesis
[gene\|0197A037D2AF049B295E1DA60187D4614B2BAC51\|pyrE]	pyrimidine biosynthesis
[gene\|5D0D0D2413377FCA92440334E92B5A27A5963D9E\|pyrF]	pyrimidine biosynthesis
[gene\|CEE04B9FED63AFEAB912791402F7578E852005D1\|pyrG]	pyrimidine biosynthesis
[gene\|40655595D0C573B4CB75FB255CBB01A6ACF1F94D\|pyrH]	pyrimidine biosynthesis
[gene\|C20A05AE4CE8AEE0DA767334935CC64106A7FCCB\|pyrK]	pyrimidine biosynthesis
[gene\|A5C26E10085868A0A193C450DF58D54C636B7C2D\|pyrP]	uracil transport in/out via proton symport
[gene\|6D9CEDC7737CCFA838EBC142CD735E066C950AD2\|pyrR]	regulation of pyrimidine biosynthesis
[gene\|D97D4CFDF7A9A48A8764738ECFD42F1D3A900BE7\|tdk]	biosynthesis of thymidine nucleotides
[gene\|6FE1D3C4D4DF86DE2D3D9A143A1DCFE120F13F5F\|thyA]	biosynthesis of thymidine nucleotides
[gene\|9F9643D51E9ABA537892B19312491697CECDDCCF\|thyB]	biosynthesis of thymidine nucleotides
[gene\|5B9984BBCEC1244628DC1467BE26976AD8E06286\|tmk]	TTP biosynthesis
[gene\|A659D9894E777D8A99707CB750DF2918AEE06CE9\|udk]	UMP synthesis
[gene\|A92A17CAE2EF33C320B958325F9728EA0FD98F85\|upp]	UMP synthesis

[category|SW.2.5.2.5|2.5.2.5. Biosynthesis/ acquisition of nucleotides/ other]

Name	Function
[gene\|3B68CE8E9A35997B45E437A316996D585E43B76B\|nrdE]	synthesis of deoxyribonucleoside triphosphates
[gene\|FD4CD7DB35AA20DBBEC0A4DA5D88282D89CCDA6D\|nrdEB]	unknown
[gene\|CD2D14FE9C10544E7C350167EBDBD941B898051D\|nrdF]	synthesis of deoxyribonucleoside triphosphates
[gene\|1EA0595C74359A36B9161CFD531CA894C5E66E25\|nrdI]	synthesis of deoxyribonucleoside triphosphates
[gene\|0472A4346ADA1DC41C9D00E8F3222A0EBB76DFA8\|rnr]	nonspecific degradation of rRNA
[gene\|DAFBC470DA0FA437B117716DE899A8D3EC454672\|yhcR]	utilization of nucleic acids in biofilms

[category|SW.2.5.2.6|2.5.2.6. Biosynthesis/ acquisition of nucleotides/ other/ based on similarity]

Name	Function
[gene\|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6\|yutK]	unknown
[gene\|CB969A2D60F106466605052299F2A5FF5A20E9ED\|yxlA]	unknown

[category|SW.2.5.3|2.5.3. Metabolism of signalling nucleotides]

Name	Function
[gene\|AFE2A9998219162FE32E95628B3CA9071099B61A\|cdaA]	synthesis of [metabolite\|c-di-AMP]
[gene\|FB23F2AB0E2A82658009D115E5876E7AF1BDE5FD\|cdaR]	regulation of c-di-AMP synthesis
[gene\|92EF98B872C1AD729B0BFAD46D3FA572E9C2AA32\|cdaS]	synthesis of [metabolite\|c-di-AMP]
[gene\|90AFF93D6E7BC993B2773C12EE400C80A87A4831\|darB]	control of [protein\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel] activity, trigger of the stringent response under conditions of potassium starvation
[gene\|C43AE224400421CCDA7022C915ECC7525E30EB1D\|dgcK]	synthesis of c-di-GMP
[gene\|4C577B2CEDD9CD2CBFAF036EF36C9EFAF16F923F\|dgcP]	synthesis of c-di-GMP
[gene\|A2E6852A5739B3C04405B98AFFC301A98E1ADCD0\|dgcW]	synthesis of c-di-GMP
[gene\|2B091CCEE9E34D659771E39B1FC9050A145048AB\|disA]	control of [wiki\|sporulation] initiation, synthesis of [metabolite\|c-di-AMP]
[gene\|9B624751E8BD3EA616B4B50633A558F4CE032E2C\|gdpP]	control of sporulation initiation, cell wall homeostasis
[gene\|F022ACB2CBB8DA46B392CE1D26474093645F26DA\|glmM]	cell wall synthesis, control of c-di-AMP synthesis
[gene\|24CC89DE55B3C19F80B11D106B9FD241174AE3E4\|lysS]	translation
[gene\|0C40455EB53D25363FC3EB0E84502A76520F5F91\|nahA]	initiation of RNA degradation
[gene\|02628F274952F9AEEE9F2224B771A4CE4AAD1C8D\|pdeH]	degradation of c-di-GMP
[gene\|8D0885839CD60C05FB806BBF08AFA05225E83B12\|pgpH]	control of c-di-AMP homeostasis
[gene\|151F226370D225776F3FE7EA4901485095F1AC45\|radA]	homologous recombination, control of c-di-AMP formation, co-ordination of responses to replicative stress and genetic recombination
[gene\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel]	synthesis and degradation of (p)[metabolite\|ppGpp], triggering the stringent response regulon
[gene\|1107A963C253FBEE8716507BD0EC0E7CD5642B12\|sasA]	ppGpp synthesis independent from stringent response
[gene\|81BCF5C08EC1A580F5E05884BA830130FC7E46E9\|sasB]	ppGpp synthesis independent from stringent response
[gene\|188742B9A0C95344D32A4C23B9C971660572CF7D\|ycnB]	secretion of cyclic di-AMP
[gene\|B791B0603042603CB5B5E03CA129B20D02BC02BC\|yfkN]	degradation of c-di-AMP
[gene\|93159DC7D5C42CFA54F66F232D73F38957243AB7\|yhcA]	secretion of cyclic di-AMP
[gene\|247C47AC70A0EA53E625871D9BC463A06E6B05FB\|yqeK]	degradation of Ap₄A, degradation of toxic side-products of [protein\|AA4BB1F5B58371D536A6BBA86F6ECB5E5BFB12A8\|nadD] activity

[category|SW.2.5.4|2.5.4. Nucleotide metabolism/ other]

Name	Function
[gene\|0E9E9615CE056BEA2B65C494D946EB45F42A3064\|cdd]	pyrimidine interconversion
[gene\|B498ED03F19B7A73878D5C947C28C2A87CAB934D\|ndk]	maintainance of an equilibrium between the concentrations of different nucleoside triphosphates
[gene\|96B48D9B984010FECD2C194D7CF3CADFC22F2AA7\|pbuE]	nucleotide metabolism
[gene\|DB52F9DB4212FABC87E41F374DCD2DEBCEEE4DF8\|ybbK]	recycling of thiouracil
[gene\|5CA17CD28A725B8D7B87B9AAA167844042439794\|yjcG]	nucleotide metabolism
[gene\|1E32B355838787D34352674595A63355609D3AC4\|yncF]	nucleotide metabolism
[gene\|B004744E17773FDEAB28FEAE98BCA3C744E63A8E\|yosS]	nucleotide metabolism
[gene\|A0CC440185318F7F8665AF7A8279C79A09E35518\|ypgQ]	degradation of excessive or abnormal nucleotides
[gene\|29A38D244A07ED0973D0846B652238524F4DBC67\|ytlP]	nucleotide metabolism

Page visits: 1911

Time of last update: 2025-02-09 12:56:07

Author of last update: ghost

Name	Function
[gene\|DD3A39A84E53A9B2ACBDD89DFAE3560E45C08DC1\|adk]	ADP formation
[gene\|1BC994DE60A7BB35DEDD7154581A396D29AA94A7\|gmk]	GTP biosynthesis
[gene\|AC67305E4C165CC1D785E49B7CD8335346134376\|guaA]	biosynthesis of GMP
[gene\|AB3D18228DB6819B0C81BC7A8BB3408A4F75DC0C\|guaB]	biosynthesis of GMP
[gene\|C333F405F597FF260FFA0EC616B8CF6BF454815B\|nupG]	purine uptake
[gene\|19BA45BD691BBA4B23C4741C63DB729AA5D30FDA\|nupN]	uptake of [metabolite\|guanosine]
[gene\|71546D1508EF17A208332E162CAE2C299987A569\|nupO]	uptake of [metabolite\|guanosine]
[gene\|0BB235F189D30C9BE798560C31DA59FF0112CFD9\|nupP]	uptake of [metabolite\|guanosine]
[gene\|7A80910F4E62BA15DE93FFC70E1908FB5CB9542D\|nupQ]	uptake of [metabolite\|guanosine]
[gene\|41DDD3AAFE89D0F52AB5ABD08CEE30A1767FFD7A\|pbuG]	hypoxanthine and guanine uptake
[gene\|7D56F85FBD3AAC66607DD7465592EEAE09D61C98\|pbuX]	xanthine uptake
[gene\|37664AAEBFFDE1F7D17EA7C032805EA051FBE6AF\|prs]	phosphoribosylpyrophosphate synthesis (biosynthesis of histidine)
[gene\|AB4B8B7325A1BF444D841EF1BBBCEC2D506AE600\|purA]	purine biosynthesis
[gene\|29FF54E2B9F4A11811F5E15885A4C02A259C7B35\|purB]	purine biosynthesis
[gene\|447D12E940C7F45B6C5015844F9DED9D513CD6E5\|purC]	purine biosynthesis
[gene\|9BBA22B09C6DD6C36E043D44B0F54BD0FFA5BA0E\|purD]	purine biosynthesis
[gene\|1A9F7847AA1EB2A264842B44CD1B1A21F0AF6E57\|purE]	purine biosynthesis
[gene\|4AA5AF9C7CE8D0A9FD3A47650ECF130BCBEE1952\|purF]	purine biosynthesis
[gene\|54CE8EB2F5D1F9AEAA497E1F60248C9B2250B01E\|purH]	purine biosynthesis
[gene\|0DA73E4D1935F6A91BE251EF2704A11DE5D81174\|purK]	purine biosynthesis
[gene\|D34203FAA84C19B34B3CB5F00AC2E2663FFA344D\|purL]	purine biosynthesis
[gene\|AD0DE9457D70DF02FA0F58867B24ABF236FAF65A\|purM]	purine biosynthesis
[gene\|7B30F27D6C459437967A64467E52961F4A9E0F2C\|purN]	purine biosynthesis
[gene\|DEE856E83E790EB57F103F7A9156408AF090995D\|purQ]	purine biosynthesis
[gene\|A8C82F5825DE0921DA6B4ACDE0CC31EC7749273C\|purR]	regulation of purine biosynthesis
[gene\|CCD4DA969086181CFA33D6D241F2CAAE02E0C758\|purS]	purine biosynthesis
[gene\|C00E34EF63B5EAE33CAD5E469893C0A5112B9F35\|purT]	purine biosynthesis
[gene\|9A399CAA672C3DF90531A7A7168916DE86EFA365\|ykkE]	purine nucleotide synthesis

Name	Function
[gene\|AFE2A9998219162FE32E95628B3CA9071099B61A\|cdaA]	synthesis of [metabolite\|c-di-AMP]
[gene\|FB23F2AB0E2A82658009D115E5876E7AF1BDE5FD\|cdaR]	regulation of c-di-AMP synthesis
[gene\|92EF98B872C1AD729B0BFAD46D3FA572E9C2AA32\|cdaS]	synthesis of [metabolite\|c-di-AMP]
[gene\|90AFF93D6E7BC993B2773C12EE400C80A87A4831\|darB]	control of [protein\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel] activity, trigger of the stringent response under conditions of potassium starvation
[gene\|C43AE224400421CCDA7022C915ECC7525E30EB1D\|dgcK]	synthesis of c-di-GMP
[gene\|4C577B2CEDD9CD2CBFAF036EF36C9EFAF16F923F\|dgcP]	synthesis of c-di-GMP
[gene\|A2E6852A5739B3C04405B98AFFC301A98E1ADCD0\|dgcW]	synthesis of c-di-GMP
[gene\|2B091CCEE9E34D659771E39B1FC9050A145048AB\|disA]	control of [wiki\|sporulation] initiation, synthesis of [metabolite\|c-di-AMP]
[gene\|9B624751E8BD3EA616B4B50633A558F4CE032E2C\|gdpP]	control of sporulation initiation, cell wall homeostasis
[gene\|F022ACB2CBB8DA46B392CE1D26474093645F26DA\|glmM]	cell wall synthesis, control of c-di-AMP synthesis
[gene\|24CC89DE55B3C19F80B11D106B9FD241174AE3E4\|lysS]	translation
[gene\|0C40455EB53D25363FC3EB0E84502A76520F5F91\|nahA]	initiation of RNA degradation
[gene\|02628F274952F9AEEE9F2224B771A4CE4AAD1C8D\|pdeH]	degradation of c-di-GMP
[gene\|8D0885839CD60C05FB806BBF08AFA05225E83B12\|pgpH]	control of c-di-AMP homeostasis
[gene\|151F226370D225776F3FE7EA4901485095F1AC45\|radA]	homologous recombination, control of c-di-AMP formation, co-ordination of responses to replicative stress and genetic recombination
[gene\|CEE73284EFC0DBE8870CE0B474922DED79475A57\|rel]	synthesis and degradation of (p)[metabolite\|ppGpp], triggering the stringent response regulon
[gene\|1107A963C253FBEE8716507BD0EC0E7CD5642B12\|sasA]	ppGpp synthesis independent from stringent response
[gene\|81BCF5C08EC1A580F5E05884BA830130FC7E46E9\|sasB]	ppGpp synthesis independent from stringent response
[gene\|188742B9A0C95344D32A4C23B9C971660572CF7D\|ycnB]	secretion of cyclic di-AMP
[gene\|B791B0603042603CB5B5E03CA129B20D02BC02BC\|yfkN]	degradation of c-di-AMP
[gene\|93159DC7D5C42CFA54F66F232D73F38957243AB7\|yhcA]	secretion of cyclic di-AMP
[gene\|247C47AC70A0EA53E625871D9BC463A06E6B05FB\|yqeK]	degradation of Ap₄A, degradation of toxic side-products of [protein\|AA4BB1F5B58371D536A6BBA86F6ECB5E5BFB12A8\|nadD] activity