SinR regulon

Regulator	SinR
Overview on the regulons (wiki page) Overview on the regulons (Excel file)

• SinR may act as transcriptional repressor at some promoters (as for the tapA promoter) and as anti-activator preventing binding of RemA for other operons (as is the case for the epsA promoter) PubMed

Genes in this regulon

Repression

• aprE
• degU
• epr
• lutA-lutB-lutC
• mstX
• rapG
• rok
• sigE
• sigF
• sigG
• slrR
• spoIIAA-spoIIAB
• spoIIGA
• spoVG
• tapA-sipW-tasA
• yugO
• yvgN
• ywbD

Anti-activation (Prevention of binding of the activator protein RemA)

• epsA-epsB-epsC-epsD-epsE-epsF-epsG-epsH-epsI-epsJ-epsK-epsL-epsM-epsN-epsO

Comments

• The SinR regulon is not expressed in rny and ymdB mutants PubMed
• Expression of the SinR regulon is enhanced upon SlrA overexpression, this can be suppressed by inactivation of either remA, remB, slrR, or sinR PubMed
• Expression of the SinR regulon is enhanced in a rpsU mutant, this can be suppressed by inactivation of remA PubMed

Related SubtiWiki pages

• biofilm formation
• RemA regulon

Important publications on the SinR regulon

<pubmed>18763711,19193632,17005971 19779461 19820159 20418391 20525796 20572937,21803996 21843271 22329926 21856853 21815947 25035996 16430695</pubmed>