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RNA polymerase

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The enzyme responsible for transcription

Components of the RNA polymerase

Core subunits

Sigma factors

  • In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)

Small accessory subunits

Other temporary components

  • NusA: essential elongation factor

References

Reviews

<pubmed> 18599813 7708009 18410247 19889534 19489723 18280161 21233849 </pubmed>

The structure of RNA polymerase

<pubmed> 12732296 12581657 11297923 </pubmed>

Important original publications: PubMed