Jump to content

T-box: Difference between revisions

From SubtiWiki
Line 31: Line 31:
* Induction by phenyalanine limitation
* Induction by phenyalanine limitation
** ''[[pheS]]-[[pheT]]''
** ''[[pheS]]-[[pheT]]''
* Induction by proline limitation
** ''[[proB]]-[[proA]]'', ''[[proI]]''


* Induction by serine limitation
* Induction by serine limitation

Revision as of 04:29, 28 May 2009

The T-box element is an RNA switch that controls genes involved in amino acid metabolism.

In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.

Genes controlled by T-box elements

  • Induction by alanine limitation
  • Induction by aspartate limitation
  • Induction by histidine limitation
  • Induction by phenyalanine limitation
  • Induction by serine limitation
  • Induction by threonine limitation
  • Induction by tyrosine limitation

Reviews on T-box regulation

<pubmed> 19258532,7527891, 8348614,17381302 </pubmed>