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* '''Description:''' write here <br/><br/>
* '''Description:''' indole-3-glycerol-phosphate synthase <br/><br/>


{| align="right" border="1" cellpadding="2"  
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|-
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || indol-3-glycerol phosphate synthase (EC 4.1.1.48)
|style="background:#ABCDEF;" align="center"| '''Product''' || indole-3-glycerol-phosphate synthase
|-
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || tryptophane synthesis
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of tryptophan
|-
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 5.535   
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 5.535   

Revision as of 09:00, 17 March 2009

  • Description: indole-3-glycerol-phosphate synthase

Gene name trpC
Synonyms
Essential no
Product indole-3-glycerol-phosphate synthase
Function biosynthesis of tryptophan
MW, pI 27 kDa, 5.535
Gene length, protein length 750 bp, 250 aa
Immediate neighbours trpF, trpD
Gene sequence (+200bp) Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induction by tryptophan ( TRAP)
  • Regulatory mechanism: TRAP: binding to the mRNA in the presence of tryptophan, this results in transcription termination
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed