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| * '''Description:''' GTPase, activity stimulated by ribosomes, may be involved in ribosome maturation <br/><br/>
| | {{#bank: cpgA}} |
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| {| align="right" border="1" cellpadding="2" | |
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''cpgA ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yloQ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || GTPase
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| |style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly, coordination of peptidoglycan deposition in the cell wall
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15780 cpgA]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=cpgA cpgA]'''
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 4.743
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 894 bp, 298 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[prkC]]'', ''[[rpe]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15780 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15780 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15780 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yloQ_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cpgA_1653103_1653999_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:cpgA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15780]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/><br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[cell wall/ other]]}},
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| {{SubtiWiki category|[[translation]]}},
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| {{SubtiWiki category|[[GTP-binding proteins]]}},
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| {{SubtiWiki category|[[phosphoproteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU15780
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| ===Phenotypes of a mutant ===
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| * forms curly cells {{PubMed|22544754}}
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15780&redirect=T BSU15780]
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13392]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' engC GTPase domain (according to Swiss-Prot)
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| ** ''in vitro'' phosphorylated on Thr-166 by [[PrkC]], dephosphorylated by [[PrpC]] {{PubMed|22544754,19246764}}
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** binds the 30S subunit of the ribosome {{PubMed|22544754}}
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| * '''[[Localization]]:'''
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15780&redirect=T BSU15780]
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| * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1T9H 1T9H]
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O34530 O34530]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15780]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:'''
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| ** ''[[prpC]]-[[prkC]]-[[cpgA]]'' {{PubMed|16025310}}
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| ** ''[[cpgA]]'' {{PubMed|16025310}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cpgA_1653103_1653999_1 cpgA] {{PubMed|22383849}}
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| * '''Sigma factor:'''
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| * '''Regulation:'''
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| ** number of protein molecules per cell (minimal medium with glucose and ammonium): 170 {{PubMed|24696501}}
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| ** number of protein molecules per cell (complex medium with amino acids, without glucose): 265 {{PubMed|24696501}}
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| [[Tony Wilkinson]], York University, U.K. [http://www.york.ac.uk/depts/chem/staff/ajw.html homepage]
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| =Your additional remarks=
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| =References=
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| ==Reviews==
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| <pubmed> 19575570 </pubmed>
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| ==Original publications==
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| <pubmed> 15223319, 16485133, 14747714,22544754, 18344364, 19246764, 19246764, 15828870, 17005971, 18344364, 18984160 </pubmed>
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| [[Category:Protein-coding genes]]
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