BceR

• Description: two-component response regulator (OmpR family), regulation of bceA-bceB in response to bacitracin, plectasin, mersacidin and actagardine
  
  

Gene name	bceR
Synonyms	ytsA
Essential	no
Product	two-component response regulator (OmpR family)
Function	resistance against toxic peptides
Gene expression levels in SubtiExpress: bceR
Interactions involving this protein in SubtInteract: BceR
MW, pI	26 kDa, 5.289
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	bceS, ytrF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics, phosphoproteins

The BceR regulon:

• bceA-bceB

The gene

Basic information

• Locus tag: BSU30400

Database entries

• BsubCyc: BSU30400

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: OmpR family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated by BceS on an Asp residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • BceS-BceR PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU30400

• Structure:

• UniProt: O34951

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: bceR-bceS PubMed

• Expression browser: bceR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>10094672,18394148,12890034,14651641, 21283517, 20606066, 17905982 25118291 22964256,21078927</pubmed>