FliM

• Description: flagellar motor switch protein, part of the basal body C-ring
  
  

Gene name	fliM
Synonyms
Essential	no
Product	flagellar motor switch protein
Function	movement and chemotaxis
Gene expression levels in SubtiExpress: fliM
MW, pI	37 kDa, 4.691
Gene length, protein length	996 bp, 332 aa
Immediate neighbours	fliL, fliY
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

CodY regulon, DegU regulon, SigD regulon, Spo0A regulon

The gene

Basic information

• Locus tag: BSU16310

Database entries

• BsubCyc: BSU16310

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: fliM family (according to Swiss-Prot)

• Paralogous protein(s): FliY

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)
  • localizes as individual spots (puncta), this erquires FliF PubMed

Database entries

• BsubCyc: BSU16310

• Structure:

• UniProt: P23453

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: part of the fla-che operon (see there for regulation)
  • flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed
  • ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed

• Expression browser: fliM PubMed

• Sigma factor:
  • flgB: SigA PubMed, SigD PubMed
  • ylxF: SigD PubMed

• Regulation: see fla-che operon

• Regulatory mechanism: see fla-che operon

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 127 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>1898932,,14651647,9657996,8157612,15175317 17850253 23190039 24386445</pubmed>