Jump to content

KinE: Difference between revisions

From SubtiWiki
No edit summary
No edit summary
 
Line 1: Line 1:
* '''Description:''' [[two-component systems|two-component]] sensor kinase, phosphorylates [[Spo0F]], part of the [[phosphorelay]] <br/><br/>
{{#bank: KinE}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''kinE''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ykrQ ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] sensor kinase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13530 kinE]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=KinE KinE]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=kinE kinE]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 85 kDa, 5.489 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2214 bp, 738 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykrP]]'', ''[[ogt]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13530 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13530 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13530 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:kinE_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=kinE_1419213_1421429_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:kinE_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13530]]
|-
|}
__TOC__
<br/><br/><br/><br/>
<br/><br/><br/><br/>
<br/><br/><br/><br/>
<br/><br/><br/><br/>
<br/><br/><br/><br/>
<br/><br/><br/><br/><br/><br/>
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[protein modification]]}},
{{SubtiWiki category|[[transcription factors and their control]]}},
{{SubtiWiki category|[[phosphorelay]]}},
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[phosphoproteins]]}}
= This gene is a member of the following [[regulons]] =
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU13530
===Phenotypes of a mutant ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13530&redirect=T BSU13530]
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/kinE-ogt.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13277]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:''' autophosphorylation, phosphorylation of [[Spo0F]]
* '''Protein family:'''
* '''Paralogous protein(s):''' [[CssS]], [[YkoH]], [[YclK]], [[YvrG]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:''' two transmembrane segments, C-terminal histidine phosphotransferase domain
* '''Modification:''' autophosphorylation on a His residue
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:''' [[KinE]]-[[Spo0F]]
* '''[[Localization]]:'''
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13530&redirect=T BSU13530]
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/O31661 O31661]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU13530]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[kinE]]-[[ogt]]'' {{PubMed|2506524}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=kinE_1419213_1421429_1 kinE] {{PubMed|22383849}}
* '''Sigma factor:''' [[SigA]] {{PubMed|2506524}}
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>10094672,11069677,2506524 , </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 16:15, 27 October 2014