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| * '''Description:''' [[Protein kinases and phosphatases|protein serine phosphatase]], energy PP2C, dephosphorylates [[RsbV]] <br/><br/>
| | {{#bank: RsbP}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''rsbP''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvfP ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || [[Protein kinases and phosphatases|protein serine phosphatase]], energy PP2C
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34110 rsbP]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RsbP RsbP]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=rsbP rsbP]'''
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 4.827
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1209 bp, 403 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rsbQ]]'', ''[[ganB]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU34110 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU34110 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU34110 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:rsbP_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsbP_3500386_3501597_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:rsbP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34110]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/><br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[protein modification]]}},
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| {{SubtiWiki category|[[sigma factors and their control]]}}
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| = This gene is a member of the following [[regulons]] =
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU34110
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU34110&redirect=T BSU34110]
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12441]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:''' dephosphorylation of [[RsbV]] in response to red light, this results in [[SigB]] activation {{PubMed|19948797}}
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:''' N-terminal PAS domain, central coiled-coil domain, C-terminal PP2C phosphatase domain
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| ** activity is stimulated upon interaction of the RsbP oligomer with RsbQ {{PubMed|21980452}}
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[RsbP]]-[[RsbV]] {{PubMed|10632888}}
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| ** [[RsbQ]]-[[RsbP]] {{PubMed|15632289,21980452}}
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| * '''[[Localization]]:'''
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU34110&redirect=T BSU34110]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O07014 O07014]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU34110]
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| * '''E.C. number:''' [http://www.expasy.org/enzyme/3.1.3.3 3.1.3.3]
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:'''
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsbP_3500386_3501597_1 rsbP] {{PubMed|22383849}}
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| * '''Sigma factor:'''
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| * '''Regulation:'''
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| * [[Chet Price]], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
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| =Your additional remarks=
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| =References=
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| ==Reviews==
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| <pubmed> 20658979 </pubmed>
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| ==Original publications==
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| '''Additional publications:''' {{PubMed|21980452}}
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| <big>''Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB'' </big>
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| <big>'''Stochastic pulse regulation in bacterial stress response.''' </big>
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| <big>Science. 2011 334:366-369. </big>
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| [http://www.ncbi.nlm.nih.gov/pubmed/21979936 PubMed:21979936]
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| <pubmed>12867438,15632289,11591687,10632888,16267279,15342585,, 19432806 , 19478430 19948797 </pubmed>
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| [[Category:Protein-coding genes]]
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