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| * '''Description:''' anti-[[sigma factor]] to [[SigV]] <br/><br/>
| | {{#bank: RsiV}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''rsiV''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yrhM ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || anti-[[sigma factor]] to [[SigV]]
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| |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigV]] activity
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27130 rsiV]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RsiV RsiV]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 5.833
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 855 bp, 285 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sigV]]'', ''[[oatA]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27130 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27130 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27130 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yrhM_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsiV_2770350_2771207_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:rsiV_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27130]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[sigma factors and their control]]}},
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| {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigV regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU27130
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27130&redirect=T BSU27130]
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sigV-yrhM.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12302]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| ** upon exposure to lysozyme, the extracellular domain of [[RsiV]] is cleaved off by an unknown protease, subsequently the N-terminal part of the protein is subject to intramemrane proteolysis by [[RasP]] {{PubMed|23687273}}
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[SigV]]-[[RsiV]], this interaction inhibits the activity of [[SigV]] {{PubMed|23687273}}
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| ** [[RasP]]-[[RsiV]], degradation of [[RsiV]] {{PubMed|23687273}}
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| * '''[[Localization]]:'''
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| ** membrane {{PubMed|23687273}}
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27130&redirect=T BSU27130]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O05403 O05403]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27130]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[sigV]]-[[rsiV]]-[[oatA]]-[[yrhK]]'' {{PubMed|21856855}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsiV_2770350_2771207_1 rsiV] {{PubMed|22383849}}
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| * '''Sigma factor:''' [[SigV]] {{PubMed|21856855}}
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| * '''Regulation:'''
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| ** induced by lysozyme ([[SigV]]) {{PubMed|21856855}}
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>14993308,16274938 20817771, 23687273</pubmed>
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| [[Category:Protein-coding genes]]
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