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MotB: Difference between revisions

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* '''Description:''' H+-coupled [[MotA]]-[[MotB]] flagellar stator <br/><br/>
{{#bank: MotB}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''motB''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''mot ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || motility protein (flagellar motor rotation)
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || [[motility and chemotaxis]]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13680 motB]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=MotB MotB]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 6.652 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 783 bp, 261 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mhqR]]'', ''[[motA]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13680 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13680 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13680 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:motB_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=motB_1433676_1434461_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:motB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13680]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[motility and chemotaxis]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigD regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU13680
===Phenotypes of a mutant ===
* loss of swimming and swarming motility {{PubMed|24296669}}
* mucoid phenotype due to the [[DegU]]-P activated overexpression of the ''[[capB]]-[[capC]]-[[capA]]-[[capE]]'' operon and resulting overproduction of poly-gamma-glutamate {{PubMed|24296669,23888912}}
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13680&redirect=T BSU13680]
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/motAB.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10689]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' OmpA-like domain (according to Swiss-Prot)
* '''Paralogous protein(s):''' [[MotS]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''[[Domains]]:'''
* '''Modification:'''
** protonation of Asp-24 is essential for torque generation {{PubMed|23888912,9573160}}
* '''[[Cofactors]]:'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:''' [[MotA]]-[[MotB]]
* '''Localization:''' cell membrane (according to Swiss-Prot)
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU13680&redirect=T BSU13680]
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P28612 P28612]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU13680]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[motA]]-[[motB]]'' {{PubMed|6313226}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=motB_1433676_1434461_-1 motB] {{PubMed|22383849}}
* '''Sigma factor:''' [[SigD]] {{PubMed|6313226}}
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:''' available in [[Nicola Stanley-Wall]]'s lab {{PubMed|23888912}}
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>6313226 24296669 23888912 9573160</pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 15:24, 4 October 2014