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* '''Description:''' ATP-dependent DNA helicase <br/><br/>
{{#bank: RecQ}}


{| align="right" border="1" cellpadding="2"
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''recQ''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''recS, ypbC ''
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || ATP-dependent DNA helicase
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|style="background:#ABCDEF;" align="center"|'''Function''' || replication reactivation pathway
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23020 recQ]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RecQ RecQ]
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 56 kDa, 6.228 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1488 bp, 496 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ypbD]]'', ''[[ypbB]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23020 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23020 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23020 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:recQ_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=recQ_2406922_2408412_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:recQ_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23020]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[DNA repair/ recombination]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU23020
===Phenotypes of a mutant ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU23020&redirect=T BSU23020]
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11407]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' RecQ subfamily (according to Swiss-Prot)
* '''Paralogous protein(s):''' [[YocI]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** [[SsbA]]-[[RecQ]] according to {{PubMed|22933559}}
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU23020&redirect=T BSU23020]
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P50729 P50729]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU23020]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:'''
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=recQ_2406922_2408412_-1 recQ] {{PubMed|22383849}}
* '''[[Sigma factor]]:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
** 1A893 (no resistance), {{PubMed|16020779}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A893&Search=1A893 BGSC]
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
==Reviews==
<pubmed>12427530 , 21047263,  22933559 </pubmed>
== Original publications ==
<pubmed>17853894,, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 11:29, 24 September 2014