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| * '''Description:''' nicotinate transporter <br/><br/>
| | {{#bank: NiaP}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''yceI''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || nicotinate transporter
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| |style="background:#ABCDEF;" align="center"|'''Function''' || uptake of niacin
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02950 niaP]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=NiaP NiaP]'''
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 9.502
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1200 bp, 400 aa
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yceH]]'', ''[[yceJ]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02950 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02950 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02950 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yceI_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yceI_317725_318927_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:niaP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02950]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[transporters/ other]]}},
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| {{SubtiWiki category|[[biosynthesis of cofactors]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[NadR regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU02950
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| ===Phenotypes of a mutant ===
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| * more sensitive to nisin {{PubMed|23980836}}
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02950&redirect=T BSU02950]
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12773]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' MFS transporter {{PubMed|18276644}}
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:''' 10 membrane-spanning domains {{PubMed|18276644}}
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:''' cell membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02950&redirect=T BSU02950]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O34691 O34691]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU02950]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[niaP]]'' {{PubMed|22383849}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yceI_317725_318927_1 niaP] {{PubMed|22383849}}
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| * '''Sigma factor:'''
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| * '''Regulation:'''
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| ** repressed in the presence of nicotinic acid ([[NadR]]) {{PubMed|18276644}}
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| * '''Regulatory mechanism:'''
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| ** [[NadR]]: transcription repression {{PubMed|18276644}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| ==Reviews==
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| <pubmed> 21953179 </pubmed>
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| ==Original publications==
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| <pubmed>18763711, 18276644 23980836 22383849</pubmed>
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| [[Category:Protein-coding genes]]
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