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YukC: Difference between revisions

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* '''Description:''' membrane pseudokinase-like protein, part of the type VII [[protein secretion]] system [[YukD]]-[[YukC]]-[[YukB]]-[[YueB]]-[[YueC]] <br/><br/>
{{#bank: YukC}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yukC''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || membrane pseudokinase-like protein, part of the type VII [[protein secretion]] system
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || export of [[YukE]]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31890 yukC]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 4.675 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1353 bp, 451 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yukB]]'', ''[[yukD]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31890 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31890 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31890 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:yukC_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yukC_3274462_3275817_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yukC_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31890]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[protein secretion]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[DegU regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU31890
===Phenotypes of a mutant ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31890&redirect=T BSU31890]
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12376]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:'''
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:'''
** membrane (according to SwissProt) {{PubMed|23861817}}
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31890&redirect=T BSU31890]
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P71070 P71070]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU31890]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[yukE]]-[[yukD]]-[[yukC]]-[[yukB]]-[[yueB]]-[[yueC]]'' {{PubMed|22383849,15576783}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yukC_3274462_3275817_-1 yukC] {{PubMed|22383849}}
* '''[[Sigma factor]]:''' [[SigA]]  {{PubMed|22383849}}
* '''Regulation:'''
** not expressed in the lab strain 168, due to lack of [[DegU]]-P {{PubMed|23861817}}
** expressed in the stationary phase {{PubMed|23861817}}
* '''Regulatory mechanism:'''
** [[DegU]]-P: transcription activation {{PubMed|23861817}}
* '''Additional information:'''
** number of protein molecules per cell (complex medium with amino acids, without glucose): 77 {{PubMed|24696501}}
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
== Reviews ==
<pubmed> 19155186 11973144 </pubmed>
== Original publications ==
<pubmed>15576783 22383849 23861817 </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 06:55, 8 May 2014