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| * '''Description:''' nutrient receptor <br/><br/>
| | {{#bank: GerKA}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''gerKA''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || nutrient receptor
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| |style="background:#ABCDEF;" align="center"|'''Function''' || [[germination]] response to the combination of glucose, <br/>fructose, aspartate, and KCl
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03700 gerKA]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=GerKA GerKA]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 60 kDa, 5.206
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1632 bp, 544 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gerKD]]'', ''[[gerKC]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03700 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03700 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03700 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:gerKA_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerKA_420110_421744_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:gerKA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03700]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[germination]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigG regulon]]}},
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| {{SubtiWiki regulon|[[SpoVT regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU03700
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03700&redirect=T BSU03700]
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gerKACB.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11392]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' gerABKA family (according to Swiss-Prot)
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| ** contains multiple membrane-spanning domains {{PubMed|23335419}}
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[GerKA]]-[[GerKB]]-[[GerKC]] (tentative receptor complex) {{PubMed|21696470}}
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| ** [[GerKA]] is part of the [[germinosome]] in the spore inner membrane {{PubMed|21696470}}
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| * '''[[Localization]]:'''
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| ** outer surface of the inner spore membrane {{PubMed|23335419,21696470}}
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03700&redirect=T BSU03700]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P49939 P49939]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU03700]
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| * '''E.C. number:'''
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| === Additional information===
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| * 700 molecules are present per spore {{PubMed|23749970}}
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| =Expression and regulation=
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| * '''Operon:''' ''[[gerKA]]-[[gerKC]]-[[gerKB]]'' (according to [http://dbtbs.hgc.jp/COG/prom/gerKACB.html DBTBS])
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerKA_420110_421744_1 gerKA] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:''' SigG {{PubMed|16707705}}
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| * '''Regulation:'''
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| ** expressed during sporulation ([[SigG]], [[SpoVT]]) {{PubMed|16707705}}
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| * '''Regulatory mechanism:'''
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| ** [[SpoVT]]: transcription repression {{PubMed|16707705}}
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| * '''Additional information:'''
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| ** 700 molecules are present per spore {{PubMed|23749970}}
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>16707705,16352818, 21696470 23335419 23396907 22343299,16740944, 23749970</pubmed>
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| [[Category:Protein-coding genes]]
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