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* '''Description:''' N-acetyl muramic acid-specific [[PTS|phosphotransferase system]], EIIBC component of the [[PTS]]<br/><br/>
{{#bank: MurP}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''murP''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ybbF''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || N-acetyl muramic acid-specific <br/>[[PTS|phosphotransferase system]], EIIBC component
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || N-acetyl muramic acid uptake and phosphorylation
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01680 murP]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=murP murP]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 8.496 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1365 bp, 455 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[amiE]]'', ''[[murR]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01680 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01680 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01680 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:ybbF_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbF_189790_191157_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:murP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01680]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[cell wall degradation/ turnover]]}},
{{SubtiWiki category|[[phosphotransferase systems]]}},
{{SubtiWiki category|[[utilization of specific carbon sources]]}},
{{SubtiWiki category|[[phosphoproteins]]}},
{{SubtiWiki category|[[Sporulation#Sporulation_proteins/_other|sporulation proteins]]}}
= This gene is a member of the following [[regulons]] =
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU01680
===Phenotypes of a mutant ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01680&redirect=T BSU01680]
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11567]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:''' transport and concomitant phosphorylation of N-acetyl muramic acid
* '''Protein family:''' [[PTS]] permease, sucrose permease (Scr) family [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed]
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:'''
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01680&redirect=T BSU01680]
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/Q797S1 Q797S1]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU01680]
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.1.69 2.7.1.69]
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[murQ]]-[[murR]]-[[murP]]-[[amiE]]-[[nagZ]]-[[ybbC]]'' {{PubMed|22383849}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbF_189790_191157_-1 murP] {{PubMed|22383849}}
* '''Sigma factor:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>10627040, 15060041 22383849</pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 12:53, 24 April 2014