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| * '''Description:''' [[ATP synthase]], part of the F1 complex (subunit beta) <br/><br/>
| | {{#bank: AtpD}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''atpD''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || [[ATP synthase]] (subunit beta))
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || [[ATP synthesis]]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36810 atpD]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=AtpD AtpD]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 4.611
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1419 bp, 473 aa
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[atpC]]'', ''[[atpG]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36810 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:atpD_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=atpD_3781491_3782912_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:atpD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36810]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[ATP synthesis]]}},
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| {{SubtiWiki category|[[membrane proteins]]}},
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| {{SubtiWiki category|[[phosphoproteins]]}},
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| [[most abundant proteins]]
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[stringent response]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU36810
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU36810&redirect=T BSU36810]
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/atp.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10821]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:''' ATP + H<sub>2</sub>O + H<sup>+</sup>(In) = ADP + phosphate + H<sup>+</sup>(Out) (according to Swiss-Prot), ATP synthesis [http://www.youtube.com/watch?v=uOoHKCMAUMc see a video]
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| * '''Protein family:''' ATPase alpha/beta chains family (according to Swiss-Prot)
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''[[Domains]]:'''
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| * '''Modification:''' phosphorylated on ser/ thr/ tyr [http://www.ncbi.nlm.nih.gov/pubmed/16493705 PubMed]
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| * '''[[Cofactors]]:'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[AtpB|A]](1)-[[AtpF|B]](2)-[[AtpE|C]](12) - [[AtpA|alpha]](3)-[[AtpD|beta]](3)-[[AtpG|gamma]]-[[AtpH|delta]]-[[AtpC|epsilon]]
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| * '''[[Localization]]:'''
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| ** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
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| ** peripheral via theF0 complex
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU36810&redirect=T BSU36810]
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| * '''Structure:''' [http://www.rcsb.org/pdb/101/motm.do?momID=72&evtc=Suggest&evta=Moleculeof%20the%20Month&evtl=OtherOptions see here an overview on ATPase structure]
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P37809 P37809]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU36810]
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| * '''E.C. number:''' [http://www.expasy.org/enzyme/3.6.3.14 3.6.3.14]
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[atpI]]-[[atpB]]-[[atpE]]-[[atpF]]-[[atpH]]-[[atpA]]-[[atpG]]-[[atpD]]-[[atpC]]'' {{PubMed|9353933}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=atpD_3781491_3782912_-1 atpD] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:'''
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| * '''Regulation:'''
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| ** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| ** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}}
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| == Reviews ==
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| <pubmed> 23356252 23341301, 23267178 22822068 21524994 19489730 17208001 16730323 </pubmed>
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| == Original publications ==
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| <pubmed>7961438,15378759,16493705 18763711, </pubmed>
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| [[Category:Protein-coding genes]]
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