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* '''Description:''' galactotriose [[ABC transporter]], binding protein <br/><br/>
{{#bank: CycB}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''cycB''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvfK ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || galactotriose [[ABC transporter]], binding protein
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || uptake of galactotriose
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34160 cycB]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=CycB CycB]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.441 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1263 bp, 421 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ganP]]'', ''[[lacR]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU34160 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU34160 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU34160 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:yvfK_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cycB_3507253_3508518_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:cycB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34160]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[ABC transporters]]}},
{{SubtiWiki category|[[utilization of specific carbon sources]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[LacR regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU34160
===Phenotypes of a mutant ===
* a ''[[cycB]]-[[ganP]]-[[ganQ]]-[[ganA]]-[[ganB]]'' mutant is impaired in the utilization of galactan {{PubMed|22893383}}
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU34160&redirect=T BSU34160]
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12436]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' bacterial solute-binding protein 1 family (according to Swiss-Prot)
* '''Paralogous protein(s):''' [[MdxE]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** ([[GanP]]-[[GanQ]])-[[CycB]] {{PubMed|10092453}}
* '''[[Localization]]:''' cell membrane (via [[GanP]]-[[GanQ]]) {{PubMed|10092453}}
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU34160&redirect=T BSU34160]
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/O07009 O07009]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU34160]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:'''  ''[[cycB]]-[[ganP]]-[[ganQ]]-[[ganA]]-[[ganB]]'' {{PubMed|9287030}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cycB_3507253_3508518_-1 cycB] {{PubMed|22383849}}
* '''Sigma factor:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
** [[LacR]]: transcription repression {{PubMed|9287030}}
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>11682178,10092453,9287030, 22893383</pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 10:07, 17 April 2014