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| * '''Description:''' probably DNA-binding protein, regulates transcription of some spore coat genes <br/><br/>
| | {{#bank: GerR}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''gerR''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ylbO''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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| |style="background:#ABCDEF;" align="center"|'''Function''' || spore coat formation and resistance of spores to lysozyme
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15090 gerR]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 7.109
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 579 bp, 193 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rpmF]]'', ''[[ylbP]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15090 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15090 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15090 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:ylbO_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ylbO_1576129_1576710_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:gerR_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15090]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[transcription factors and their control]]}},
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| {{SubtiWiki category|[[sporulation proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigE regulon]]}},
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| {{SubtiWiki regulon|[[SpoIIID regulon]]}}
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| =The [[GerR regulon]]=
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU15090
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15090&redirect=T BSU15090]
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gerR.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13367]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:''' phosphorylated on Ser-180 {{PubMed|20509597}}
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15090&redirect=T BSU15090]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O34549 O34549]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15090]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''gerR'' (according to [http://dbtbs.hgc.jp/COG/prom/gerR.html DBTBS])
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ylbO_1576129_1576710_1 gerR] {{PubMed|22383849}}
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| * '''Sigma factor:''' [[SigE]] {{PubMed|15699190}}
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| * '''Regulation:'''
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| ** expressed during sporulation in the mother cell ([[SigE]], [[SpoIIID]]) {{PubMed|15699190,20435725}}
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| ** repressed by glucose (3.2-fold) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]
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| ** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]
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| * '''Regulatory mechanism:'''
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| ** [[SpoIIID]]: transcription activation {{PubMed|20435725}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>15383836,15621419,20435725,12850135 12107147, 20509597 </pubmed>
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| [[Category:Protein-coding genes]]
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