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| * '''Description:''' general stress protein, similar to pentose transporter, required for protection against paraquat stress <br/><br/>
| | {{#bank: CsbC}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''csbC''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yxcC ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || putative pentose transporter
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| |style="background:#ABCDEF;" align="center"|'''Function''' || protection against paraquat stress
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39810 csbC]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=CsbC CsbC]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 9.943
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1383 bp, 461 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yxcD]]'', ''[[htpG]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39810 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:csbC_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=csbC_4088002_4089387_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:csbC_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39810]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[transporters/ other]]}},
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| {{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
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| {{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigB regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU39810
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11360]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):''' [[AraE]], [[CsbC]], [[IolT]], [[YfiG]], [[YncC]], [[YwtG]]
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| ** contains 12 trans-membrane domains {{PubMed|23180473}}
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[CsbC]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
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| ** [[CsbC]]-[[TatAD]] {{PubMed|23180473}}
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| ** [[CsbC]]-[[TatCD]] {{PubMed|23180473}}
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| * '''[[Localization]]:'''
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| ** homogeneously distributed in the cell membrane {{PubMed|23180473}}
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P46333 P46333]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU39810]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:'''
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=csbC_4088002_4089387_1 csbC] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed]
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| * '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed]
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>10376822,21630458,15805528, 23180473 22582280</pubmed>
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| [[Category:Protein-coding genes]]
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