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RbsC: Difference between revisions

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* '''Description:''' ribose [[ABC transporter]] (permease) <br/><br/>
{{#bank: RbsC}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rbsC''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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|style="background:#ABCDEF;" align="center"| '''Product''' || ribose [[ABC transporter]] (permease)
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|style="background:#ABCDEF;" align="center"|'''Function''' || ribose uptake
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35950 rbsC]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RbsC RbsC]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=rbsC rbsC]'''
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 10.309 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 966 bp, 322 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rbsA]]'', ''[[rbsB]]''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35950 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35950 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35950 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:rbsC_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rbsC_3705165_3706133_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:rbsC_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35950]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[ABC transporters]]}},
{{SubtiWiki category|[[utilization of specific carbon sources]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[AbrB regulon]]}},
{{SubtiWiki regulon|[[CcpA regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU35950
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rbsRKDACB.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10880]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' AraH/rbsC subfamily (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** [[RbsA]](2)-([[RbsC]]-[[RbsD]])-[[RbsB]] {{PubMed|10092453}}
* '''[[Localization]]:''' cell membrane {{PubMed|10092453}}
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P36948 P36948]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU35950]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[rbsR]]-[[rbsK]]-[[rbsD]]-[[rbsA]]-[[rbsC]]-[[rbsB]]'' {{PubMed|7921236}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rbsC_3705165_3706133_1 rbsC] {{PubMed|22383849}}
* '''Sigma factor:''' [[SigA]] {{PubMed|7511775}}
* '''Regulation:'''
** repressed by glucose ([[CcpA]]) {{PubMed|7921236}}
** expressed upon transition into the stationary phase ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
* '''Regulatory mechanism:'''
** [[CcpA]]: transcription repression {{PubMed|7921236}}
** [[AbrB]]:  transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>10092453,16872404,7511775,7592460,7921236, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 14:58, 2 April 2014