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* '''Description:''' nutrient receptor, [[germination]] response to the combination of glucose, fructose, and KCl <br/><br/>
{{#bank: GerBB}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''gerBB''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || nutrient receptor
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || [[germination]]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35810 gerBB]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=GerBB GerBB]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 9.889 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1104 bp, 368 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gerBA]]'', ''[[gerBC]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35810 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:gerBB_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerBB_3690269_3691375_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:gerBB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35810]]
|-
|}
__TOC__
<br/><br/><br/><br/>
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<br/><br/>
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[germination]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigG regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU35810
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gerBABC.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10641]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:'''
** [[APC superfamily of transport proteins|amino acid, polyamine, organocation (APC) superfamily of transporters]], [http://www.tcdb.org/search/result.php?tc=2.A.3 TC 2.A.3]
* '''Paralogous protein(s):''' [[GerAB]], [[GerKB]], [[YndE]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** [[GerBA]]-[[GerBB]]-[[GerBC]] (tentative receptor complex)  {{PubMed|21696470}}
** [[GerBB]] is part of the [[germinosome]] in the spore inner membrane {{PubMed|21696470}}
* '''[[Localization]]:'''
** spore inner membrane {{PubMed|21696470}}
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P39570 P39570]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU35810]
* '''[http://www.tcdb.org/ T.C.] number:''' [http://www.tcdb.org/search/result.php?tc=2.A.3.9.2 2.A.3.9.2]
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[gerBA]]-[[gerBB]]-[[gerBC]]'' {{PubMed|8012571}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerBB_3690269_3691375_1 gerBB] {{PubMed|22383849}}
* '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190,8012571}}
* '''Regulation:'''
** expressed late during sporulation in the forespore ([[SigG]]) {{PubMed|15699190,8012571}}
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
'''Additional publications:''' {{PubMed|16740944}}
<pubmed>10348844,12670969,15774895,7812448,8012571,16352818, 21696470 23396907 </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 14:57, 2 April 2014