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RsbQ: Difference between revisions

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* '''Description:''' alpha/beta hydrolase, required for [[RsbP]] activation <br/><br/>
{{#bank: RsbQ}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rsbQ''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvfQ ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || alpha/beta hydrolase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34100 rsbQ]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RsbQ RsbQ]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=rsbQ rsbQ]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 5 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 807 bp, 269 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvfR]]'', ''[[rsbP]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU34100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU34100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU34100 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:rsbQ_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsbQ_3499541_3500350_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:rsbQ_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34100]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[sigma factors and their control]]}}
= This gene is a member of the following [[regulons]] =
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU34100
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12442]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' AB hydrolase superfamily (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** [[RsbQ]]-[[RsbP]] {{PubMed|15632289,21980452}}
* '''[[Localization]]:'''
=== Database entries ===
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1WOM 1WOM] {{PubMed|15632289}}
* '''UniProt:''' [http://www.uniprot.org/uniprot/O07015 O07015]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU34100]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:'''
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rsbQ_3499541_3500350_1 rsbQ] {{PubMed|22383849}}
* '''Sigma factor:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
* [[Chet Price]], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
=Your additional remarks=
=References=
'''Additional publications:''' {{PubMed|21980452}}
<big>''Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB''  </big>
<big>'''Stochastic pulse regulation in bacterial stress response.''' </big>
<big>Science. 2011 334:366-369. </big>
[http://www.ncbi.nlm.nih.gov/pubmed/21979936 PubMed:21979936]
<pubmed>15632289,11591687,, 19432806  </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 14:48, 2 April 2014