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| * '''Description:''' transcription repressor of the multidrug-resistance ''[[mdtR]]-[[mdtP]]'' operon <br/><br/>
| | {{#bank: MdtR}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''mdtR''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yusO''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || transcription repressor (MarR family)
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the multidrug-resistance ''[[mdtR]]-[[mdtP]]'' operon
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU32870 mdtR]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 6.376
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 465 bp, 155 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yusN]]'', ''[[mdtP]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32870 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32870 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32870 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yusO_context.gif]]
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| |}
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| __TOC__
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[transcription factors and their control]]}},
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| {{SubtiWiki category|[[resistance against toxins/ antibiotics]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[MdtR regulon]]}}
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| =The [[MdtR regulon]]:=
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| * ''[[mdtR]]-[[mdtP]]''
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:'''
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG14027]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| === Database entries ===
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| * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1S3J 1S3J]
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O32181 O32181]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU32870]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[mdtR]]-[[mdtP]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/19286808 PubMed]
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| * '''[[Sigma factor]]:'''
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| * '''Regulation:'''
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| * '''Regulatory mechanism:''' repression by MdtR [http://www.ncbi.nlm.nih.gov/sites/entrez/19286808 PubMed]
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:''' GP1115 (spc), available in [[Stülke]] lab
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>19286808, </pubmed>
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| [[Category:Protein-coding genes]]
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