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YtrC: Difference between revisions

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* '''Description:''' [[ABC transporter]] (hydrophobic protein, probably channel protein) <br/><br/>
{{#bank: YtrC}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ytrC''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] <br/>(hydrophobic protein, probably channel protein)
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30440 ytrC]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YtrC YtrC]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=ytrC ytrC]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 7.744 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 984 bp, 328 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytrD]]'', ''[[ytrB]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30440 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30440 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30440 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:ytrC_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytrC_3116996_3117982_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ytrC_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30440]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[ABC transporters]]}},
{{SubtiWiki category|[[cold stress proteins]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[YtrA regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU30440
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ytrABCDEF.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13913]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' ABC-5 integral membrane protein family (according to Swiss-Prot)
* '''Paralogous protein(s):''' [[YtrD]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** ([[YtrB]]-[[YtrE]])-([[YtrC]]-[[YtrD]])-[[YtrF]] {{PubMed|10986249}}
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34898 O34898]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU30440]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[ytrG]]-[[ytrA]]-[[ytrB]]-[[ytrC]]-[[ytrD]]-[[ytrE]]-[[ytrF]]''  {{PubMed|10986249,21856850}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytrC_3116996_3117982_-1 ytrC] {{PubMed|22383849}}
* '''Sigma factor:''' [[SigA]]  {{PubMed|10986249}}
* '''Regulation:'''
** induced by ramoplanin ([[YtrA]]) {{PubMed|21856850}}
** expressed early in the stationary phase  {{PubMed|10986249}}
** induced by cold shock (5-fold) {{PubMed|12399512}}
* '''Regulatory mechanism:'''
** [[YtrA]]: transcription repression {{PubMed|10986249,21856850}}
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
'''Additional publications:''' {{PubMed|21856850}}
<pubmed>10986249,10092453,12399512 </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 14:34, 2 April 2014