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MutSB: Difference between revisions

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* '''Description:''' probable DNA mismatch repair protein <br/><br/>
{{#bank: MutSB}}


{| align="right" border="1" cellpadding="2"
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''mutSB''
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yshD ''
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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|style="background:#ABCDEF;" align="center"| '''Product''' || probable DNA mismatch repair protein
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|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28580 mutSB]
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 87 kDa, 5.79 
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2355 bp, 785 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yshE]]'', ''[[polX]]''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28580 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28580 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28580 DNA_with_flanks]
|-
|-
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|colspan="2" | '''Genetic context''' <br/> [[Image:mutSB_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mutSB_2920936_2923293_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:mutSB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28580]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[DNA repair/ recombination]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU28580
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12328]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' DNA mismatch repair mutS family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:'''
** cell membrane (according to Swiss-Prot)
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P94545 P94545]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU28580]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:'''
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mutSB_2920936_2923293_-1 mutSB] {{PubMed|22383849}}
* '''[[Sigma factor]]:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
** 1A845 ( ''mutSB''::''cat''), {{PubMed|11254128}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A845&Search=1A845 BGSC]
** 1A845 ( ''mutSB''::''cat''), {{PubMed|11254128}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A845&Search=1A845 BGSC]
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
[[Alessandra Albertini]], University of Pavia, Italy [http://www-1.unipv.it/genbiom/albertini.html homepage]
=Your additional remarks=
=References=
==Reviews==
<pubmed> 22933559 </pubmed>
== Original publications ==
<pubmed>11254128,, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 14:27, 2 April 2014