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| * '''Description:''' cytochrome c550 <br/><br/>
| | {{#bank: CccA}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''cccA''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || cytochrome c550
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| |style="background:#ABCDEF;" align="center"|'''Function''' || respiration
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25190 cccA]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 5.276
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 360 bp, 120 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trmK]]'', ''[[sigA]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25190 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25190 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25190 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:cccA_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cccA_2599523_2599885_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:cccA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25190]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[respiration]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[CcpA regulon]]}},
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| {{SubtiWiki regulon|[[AbrB regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU25190
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10315]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| ** transmembrane domain at the N-terminus (aa 5 -25) {{PubMed|2166045}}
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| * '''Modification:'''
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| * '''Cofactor(s):''' heme c {{PubMed|2166045}}
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| ** cell membrane {{PubMed|2166045}}
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P24469 P24469]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU25190]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[cccA]]'' {{PubMed|22383849}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cccA_2599523_2599885_-1 cccA] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|11361075}}
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| * '''Regulation:'''
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| ** carbon catabolite repression ([[CcpA]]) {{PubMed|22900538,11361075,12850135}}
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| * '''Regulatory mechanism:'''
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| ** [[CcpA]]: transcription repression, cre site overlaps -35 region of the promoter {{PubMed|11361075}}
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| ** [[AbrB]]: transcription repression {{PubMed|20817675}}
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| * '''Additional information:''' the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>2171986,10024472,12884008,8383048,2166045,12850135 11361075, 22900538 22900538 22383849 20817675 10473570 </pubmed>
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| [[Category:Protein-coding genes]]
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