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AcpK: Difference between revisions

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* '''Description:''' acyl carrier protein <br/><br/>
{{#bank: AcpK}}


{| align="right" border="1" cellpadding="2"
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''acpK''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || acyl carrier protein
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|style="background:#ABCDEF;" align="center"|'''Function''' || polyketide biosynthesis
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17130 acpK]
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 4.106 
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 246 bp, 82 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pksE]]'', ''[[pksF]]''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17130 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17130 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17130 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:acpK_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=acpK_1788469_1788717_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:acpK_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17130]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[miscellaneous metabolic pathways]]}},
{{SubtiWiki category|[[biosynthesis of antibacterial compounds]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[AbrB regulon]]}},
{{SubtiWiki regulon|[[CodY regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU17130
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG14186]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:'''
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''[[Domains]]:'''
* '''Modification:'''
* '''[[Cofactors]]:'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:'''
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/Q7PC63 Q7PC63]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU17130]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[pksC]]-[[pksD]]-[[pksE]]-[[acpK]]-[[pksF]]-[[pksG]]-[[pksH]]-[[pksI]]-[[pksJ]]-[[pksL]]-[[pksM]]-[[pksN]]-[[pksR]]'' {{PubMed|22383849}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=acpK_1788469_1788717_1 acpK] {{PubMed|22383849}}
* '''[[Sigma factor]]:'''
* '''Regulation:'''
** expressed during the transition from growth to stationary phase ([[AbrB]], [[CodY]]) {{PubMed|24187085}}
* '''Regulatory mechanism:'''
** [[AbrB]]: transcription repression {{PubMed|24187085}}
** [[CodY]]: transcription activation {{PubMed|24187085}}
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>11489886,22383849 24187085, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 13:47, 2 April 2014