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| * '''Description:''' required for spore cortex peptidoglycan synthesis <br/><br/>
| | {{#bank: SpoVE}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''spoVE''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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| |style="background:#ABCDEF;" align="center"|'''Function''' || spore cortex peptidoglycan synthesis
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15210 spoVE]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SpoVE SpoVE]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=spoVE spoVE]'''
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 9.853
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1098 bp, 366 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[murD]]'', ''[[murG]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15210 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15210 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15210 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:spoVE_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVE_1590317_1591417_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:spoVE_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15210]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/><br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[cell wall synthesis]]}},
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| {{SubtiWiki category|[[biosynthesis of cell wall components]]}},
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| {{SubtiWiki category|[[sporulation proteins]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigE regulon]]}},
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| {{SubtiWiki regulon|[[SpoIIID regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU15210
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/murE-mraY-murD-spoVE-murG-murB-divIB-ylxWX-sbp.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10226]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)
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| * '''Paralogous protein(s):''' [[FtsW]], [[RodA]]
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[SpoVD]]-[[SpoVE]] {{PubMed|20417640}}, this protects [[SpoVE]] from proteolytic degradation {{PubMed|20417640}}
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| * '''[[Localization]]:''' integral membrane protein, forespore [http://www.ncbi.nlm.nih.gov/sites/entrez/17981970 PubMed]
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P07373 P07373]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15210]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:'''
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| ** ''[[murE]]-[[mraY]]-[[murD]]-[[spoVE]]-[[murG]]-[[murB]]-[[divIB]]-[[ylxW]]-[[ylxX]]-[[sbp]]'' {{PubMed|1391053}}
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| ** ''[[spoVE]]-[[murG]]-[[murB]]-[[divIB]]-[[ylxW]]-[[ylxX]]-[[sbp]]'' {{PubMed|1391053}}
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| ** ''[[spoVE]]'' {{PubMed|1391053}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVE_1590317_1591417_1 spoVE] {{PubMed|22383849}}
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| * '''Sigma factor:'''
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| ** ''[[spoVE]]'': [[SigE]] {{PubMed|8320223}}
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| * '''Regulation:'''
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| ** expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell ([[SigE]]) {{PubMed|1391053}}
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| * '''Regulatory mechanism:'''
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| ** [[SpoIIID]]: transcription repression {{PubMed|15383836}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>20417640 ,17981970, 8320223 1391053 15383836</pubmed>
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| [[Category:Protein-coding genes]]
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