GerR

• Description: probably DNA-binding protein, regulates transcription of some spore coat genes
  
  

Gene name	gerR
Synonyms	ylbO
Essential	no
Product	unknown
Function	spore coat formation and resistance of spores to lysozyme
Gene expression levels in SubtiExpress: gerR
MW, pI	22 kDa, 7.109
Gene length, protein length	579 bp, 193 aa
Immediate neighbours	rpmF, ylbP
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: BSU15090

Database entries

• BsubCyc: BSU15090

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on Ser-180 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU15090

• Structure:

• UniProt: O34549

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerR (according to DBTBS)

• Expression browser: gerR PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigE, SpoIIID) PubMed
  • repressed by glucose (3.2-fold) PubMed
  • repressed by casamino acids PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>15383836,15621419,20435725,12850135 12107147, 20509597 </pubmed>