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| * '''Description:''' S protein of tryptophan [[ECF transporter]] <br/><br/>
| | {{#bank: TrpP}} |
| {| align="right" border="1" cellpadding="2" | |
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''trpP''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yhaG''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || S protein of tryptophan [[ECF transporter]]
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || tryptophan uptake
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10010 trpP]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=TrpP TrpP]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=trpP trpP]'''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 11.155
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 516 bp, 172 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhzF]]'', ''[[serC]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10010 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10010 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10010 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yhaG_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=trpP_1074646_1075164_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:trpP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10010]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[ECF transporter]]}},
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| {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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|
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[TRAP regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU10010
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yhaG.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12983]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' trpP transporter family (according to Swiss-Prot)
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''[[Domains]]:'''
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| * '''Modification:'''
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| * '''[[Cofactors]]:'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[YbaF]]-[[TrpP]] {{PubMed|20497229}}
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| * '''[[Localization]]:'''
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| ** cell membrane (according to Swiss-Prot)
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O07515 O07515]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU10010]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[trpP]]'' {{PubMed|10735881}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=trpP_1074646_1075164_-1 trpP] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|10735881}}
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| * '''Regulation:'''
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| ** induced in the absence of tryptophan ([[MtrB]]) {{PubMed|10735881}}
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| * '''Regulatory mechanism:'''
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| ** [[MtrB]]: translation inhibition at an [[RNA switch]], the [[MtrB]] binding site overlaps the Shine-DAlgarno sequence and translation initation region, [[MtrB]] binds in the presence of tryptophan {{PubMed|10735881}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| ==Reviews==
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| <pubmed> 20497229 22574898 24362466 </pubmed>
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| ==Original publications==
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| <pubmed>10735881,14702295 , </pubmed>
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| [[Category:Protein-coding genes]]
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