RsbR: Difference between revisions
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=== Database entries === | === Database entries === | ||
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU04670&redirect=T BSU04670] | |||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rsbRSTUVW-sigB-rsbX.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rsbRSTUVW-sigB-rsbX.html] | ||
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=== Database entries === | === Database entries === | ||
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU04670&redirect=T BSU04670] | |||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BNL 2BNL] (N-terminal domain), [http://www.rcsb.org/pdb/explore.do?structureId=3VY9 3VY9] (complete stressosome) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2BNL 2BNL] (N-terminal domain), [http://www.rcsb.org/pdb/explore.do?structureId=3VY9 3VY9] (complete stressosome) | ||
Revision as of 13:02, 2 April 2014
- Description: activator of RsbT kinase activity, stressosome sensor protein
| Gene name | rsbR |
| Synonyms | ycxR, rsbRA |
| Essential | no |
| Product | activator of RsbT kinase activity, stressosome sensor protein |
| Function | control of SigB activity |
| Gene expression levels in SubtiExpress: rsbR | |
| Interactions involving this protein in SubtInteract: RbsR | |
| Metabolic function and regulation of this protein in SubtiPathways: rsbR | |
| MW, pI | 30 kDa, 4.731 |
| Gene length, protein length | 822 bp, 274 aa |
| Immediate neighbours | ndoA, rsbS |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Categories containing this gene/protein
sigma factors and their control, phosphoproteins, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04670
Phenotypes of a mutant
Database entries
- BsubCyc: BSU04670
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- RsbRA is composed of an N-terminal nonheme globin domain and a highly conserved C-terminal STAS (Sulphate Transporter and AntiSigma factor antagonist) domain. The C-terminal STAS domain is the target of the serine/threonine-specific kinase RsbT (see below).
- Effectors of protein activity:
- component of the stressosome
Database entries
- BsubCyc: BSU04670
- UniProt: P42409
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Bill Haldenwang, San Antonio, USA
- Chet Price, Davis, USA homepage
- Rick Lewis, Newcastle, UK homepage
Your additional remarks
References
Reviews
<pubmed>19704888 16319496 20658979 23416074 </pubmed>
Original Articles
<pubmed>8002610,8682769,8682789, 17726680,10781545,15583165, 8824586,10329124,17158665, 9179850,8808936,15312768, 11244072,15342582,15378759, 12950928, 15466036, 9179850, 8955331, 18832644 ,17726680 ,17218307 20019076 21602359 23320651,21362065,20935101,22287516,22609918 24599254 </pubmed>