Revision as of 07:39, 31 March 2014

Description: transcriptional repressor (GntR family) of the gamA-gamP operon

Gene name	gamR
Synonyms	ybgA
Essential	no
Product	transcriptional regulator (GntR family)
Function	regulation of glucosamine utilization
*Gene expression levels in SubtiExpress*: gamR
MW, pI	26 kDa, 5.559
Gene length, protein length	705 bp, 235 aa
Immediate neighbours	gamA, ybgB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance PubMed

Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

GamR regulon

The GamR regulon:

gamA-gamP, gamR-ybgB

The gene

Basic information

Locus tag: BSU02370

Phenotypes of a mutant

Database entries

DBTBS entry: no entry

SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

Catalyzed reaction/ biological activity:

Protein family: GntR family of transcription factors

Paralogous protein(s):

Extended information on the protein

Kinetic information:

Domains:

Modification:

Cofactors:

Effectors of protein activity:

Interactions:

Localization:

Database entries

Structure:

UniProt: O31459

KEGG entry: [2]

E.C. number:

Additional information

Expression and regulation

Operon: gamR-ybgB PubMed

Expression browser: gamR PubMed

Sigma factor: SigA PubMed

Regulation:
- induced by glucosamine (GamR) PubMed

Regulatory mechanism:
- GamR: transcription repression PubMed

Additional information:

Biological materials

Mutant:

Expression vector:

lacZ fusion:

GFP fusion:

two-hybrid system:

Antibody:

Labs working on this gene/protein

Your additional remarks

References

@@ Line 4: / Line 4: @@
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''ybgA''
+|''gamR''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ybgA ''
 |-
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of glucosamine utilization
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02370 ybgA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02370 gamR]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 5.559
@@ Line 43: / Line 43: @@
 = This gene is a member of the following [[regulons]] =
-{{SubtiWiki regulon|[[YbgA regulon]]}}
+{{SubtiWiki regulon|[[GamR regulon]]}}
-= The [[YbgA regulon]]: =
+= The [[GamR regulon]]: =
-* ''[[gamA]]-[[gamP]]'', ''[[ybgA]]-[[ybgB]]''
+* ''[[gamA]]-[[gamP]]'', ''[[gamR]]-[[ybgB]]''
 =The gene=
@@ Line 62: / Line 62: @@
 === Additional information===
 =The protein=
@@ Line 72: / Line 69: @@
 * '''Catalyzed reaction/ biological activity:'''
-* '''Protein family:'''
+* '''Protein family:''' [[GntR family]] of transcription factors
 * '''Paralogous protein(s):'''
@@ Line 80: / Line 77: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 106: / Line 103: @@
 =Expression and regulation=
-* '''Operon:''' ''[[ybgA]]-[[ybgB]]'' {{PubMed|23667565}}
+* '''Operon:''' ''[[gamR]]-[[ybgB]]'' {{PubMed|23667565}}
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybgA_257791_258498_1 ybgA] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybgA_257791_258498_1 gamR] {{PubMed|22383849}}
 * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|23667565}}
 * '''Regulation:'''
-** induced by glucosamine ([[YbgA]]) {{PubMed|23667565}}
+** induced by glucosamine ([[GamR]]) {{PubMed|23667565}}
 * '''Regulatory mechanism:'''
-** [[YbgA]]: transcription repression {{PubMed|23667565}}
+** [[GamR]]: transcription repression {{PubMed|23667565}}
 * '''Additional information:'''
@@ Line 139: / Line 136: @@
 =References=
-<pubmed> 10627040 23667565 </pubmed>
+<pubmed> 10627040 23667565 24673833 </pubmed>
 [[Category:Protein-coding genes]]