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ComFA: Difference between revisions

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* '''Description:''' late competence protein required for DNA binding and uptake <br/><br/>
* '''Description:''' membrane-associated ATPase, may provide energy for DNA transport<br/><br/>


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* '''Kinetic information:'''
* '''Kinetic information:'''


* '''Domains:'''  
* '''[[Domains]]:'''  


* '''Modification:'''
* '''Modification:'''
** phosphorylated on Arg-20, Arg-186, and Arg-446 {{PubMed|22517742}}
** phosphorylated on Arg-20, Arg-186, and Arg-446 {{PubMed|22517742}}


* '''Cofactor(s):'''
* '''[[Cofactors]]:'''


* '''Effectors of protein activity:'''
* '''Effectors of protein activity:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comFA_3642167_3643558_-1 comFA] {{PubMed|22383849}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comFA_3642167_3643558_-1 comFA] {{PubMed|22383849}}


* '''Sigma factor:'''  ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}
* '''[[Sigma factor]]:'''  ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}


* '''Regulation:'''  
* '''Regulation:'''  

Revision as of 11:17, 16 March 2014

  • Description: membrane-associated ATPase, may provide energy for DNA transport

Gene name comFA
Synonyms
Essential no
Product ATP-binding protein
Function genetic competence
Gene expression levels in SubtiExpress: comFA
Interactions involving this protein in SubtInteract: ComFA
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 52 kDa, 9.824
Gene length, protein length 1389 bp, 463 aa
Immediate neighbours comFB, yviA
Sequences Protein DNA DNA_with_flanks
Genetic context
This image was kindly provided by SubtiList
Expression at a glance   PubMed















Categories containing this gene/protein

genetic competence, membrane proteins, phosphoproteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU35470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: helicase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
    • phosphorylated on Arg-20, Arg-186, and Arg-446 PubMed
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

<pubmed> 15083159 </pubmed>

Original publications

Additional publications: PubMed <pubmed>11814663,8412657,7984101,16009133,8045895,17630974, 21278288 22517742</pubmed>