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PurS: Difference between revisions

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= [[Categories]] containing this gene/protein =
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[biosynthesis/ acquisition of nucleotides]]}}
{{SubtiWiki category|[[biosynthesis/ acquisition of nucleotides]]}},
[[most abundant proteins]]


= This gene is a member of the following [[regulons]] =
= This gene is a member of the following [[regulons]] =
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=== Additional information===
=== Additional information===


=The protein=
=The protein=
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* '''Kinetic information:'''
* '''Kinetic information:'''


* '''Domains:'''  
* '''[[Domains]]:'''  


* '''Modification:'''
* '''Modification:'''


* '''Cofactor(s):'''
* '''[[Cofactors]]:'''


* '''Effectors of protein activity:'''
* '''Effectors of protein activity:'''
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* '''Additional information:'''
* '''Additional information:'''
** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}}


=Biological materials =
=Biological materials =
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=References=
=References=


<pubmed>15301532,15301530,10784038,3036807,,7638212, </pubmed>
<pubmed>15301532,15301530,10784038,3036807,,7638212, 15378759</pubmed>


[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 16:41, 5 March 2014

  • Description: phosphoribosylformylglycinamidine synthase

Gene name purS
Synonyms yexA
Essential no
Product phosphoribosylformylglycinamidine synthase
Function purine biosynthesis
Gene expression levels in SubtiExpress: purS
Interactions involving this protein in SubtInteract: PurS
Metabolic function and regulation of this protein in SubtiPathways:
purS
MW, pI 9 kDa, 4.594
Gene length, protein length 252 bp, 84 aa
Immediate neighbours purC, purQ
Sequences Protein DNA DNA_with_flanks
Genetic context
This image was kindly provided by SubtiList
Expression at a glance   PubMed















Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, most abundant proteins

This gene is a member of the following regulons

G-box, PurR regulon

The gene

Basic information

  • Locus tag: BSU06460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0062 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of purine nucleotides (PurR) PubMed
    • repressed in the presence of adenine or adenosine(PurR) PubMed
    • repressed in the presence of guanine(G-box) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>15301532,15301530,10784038,3036807,,7638212, 15378759</pubmed>