PurH: Difference between revisions
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[biosynthesis/ acquisition of nucleotides]]}} | {{SubtiWiki category|[[biosynthesis/ acquisition of nucleotides]]}}, | ||
[[most abundant proteins]] | |||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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=== Additional information=== | === Additional information=== | ||
=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
* '''Domains:''' | * '''[[Domains]]:''' | ||
* '''Modification:''' | * '''Modification:''' | ||
* ''' | * '''[[Cofactors]]:''' | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=purH_708594_710132_1 purH] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=purH_708594_710132_1 purH] {{PubMed|22383849}} | ||
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/3036807 PubMed] | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/3036807 PubMed] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Additional information:''' | * '''Additional information:''' | ||
** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}} | |||
=Biological materials = | =Biological materials = | ||
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=References= | =References= | ||
<pubmed>3036807,12923093,,7638212, </pubmed> | <pubmed>3036807,12923093,15378759,7638212, </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:24, 5 March 2014
- Description: phosphoribosylaminoimidazole carboxamide formyltransferase
| Gene name | purH |
| Synonyms | purJ |
| Essential | no |
| Product | phosphoribosylaminoimidazole carboxamide formyltransferase and inosine-monophosphate cyclohydrolase |
| Function | purine biosynthesis |
| Gene expression levels in SubtiExpress: purH | |
| Metabolic function and regulation of this protein in SubtiPathways: purH | |
| MW, pI | 55 kDa, 5.133 |
| Gene length, protein length | 1536 bp, 512 aa |
| Immediate neighbours | purN, purD |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06520
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (according to Swiss-Prot)
- Protein family: purH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- UniProt: P12048
- KEGG entry: [3]
- E.C. number: 2.1.2.3
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
<pubmed>3036807,12923093,15378759,7638212, </pubmed>