HisF: Difference between revisions
No edit summary |
No edit summary |
||
| Line 37: | Line 37: | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/> | |||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}} | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | ||
[[most abundant proteins]] | |||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 64: | Line 61: | ||
=== Additional information=== | === Additional information=== | ||
=The protein= | =The protein= | ||
| Line 82: | Line 76: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
* '''Domains:''' | * '''[[Domains]]:''' | ||
* '''Modification:''' | * '''Modification:''' | ||
* ''' | * '''[[Cofactors]]:''' | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| Line 112: | Line 106: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hisF_3583562_3584320_-1 hisF] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hisF_3583562_3584320_-1 hisF] {{PubMed|22383849}} | ||
* '''Sigma factor:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' repressed by casamino acids {{PubMed|12107147}} | * '''Regulation:''' repressed by casamino acids {{PubMed|12107147}} | ||
| Line 119: | Line 113: | ||
* '''Additional information:''' | * '''Additional information:''' | ||
** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}} | |||
=Biological materials = | =Biological materials = | ||
| Line 140: | Line 135: | ||
=References= | =References= | ||
<pubmed>12107147, </pubmed> | <pubmed>12107147, 15378759</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:22, 5 March 2014
- Description: cyclase-like protein
| Gene name | hisF |
| Synonyms | |
| Essential | no |
| Product | cyclase-like protein |
| Function | biosynthesis of histidine |
| Gene expression levels in SubtiExpress: hisF | |
| Metabolic function and regulation of this protein in SubtiPathways: hisF | |
| MW, pI | 27 kDa, 5.238 |
| Gene length, protein length | 756 bp, 252 aa |
| Immediate neighbours | hisI, hisA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34870
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + L-glutamine = imidazole-glycerol phosphate + 5-aminoimidazol-4-carboxamide ribonucleotide + L-glutamate + H2O (according to Swiss-Prot)
- Protein family: hisA/hisF family (according to Swiss-Prot)
- Paralogous protein(s): HisA
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O34727
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation: repressed by casamino acids PubMed
- Regulatory mechanism:
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
<pubmed>12107147, 15378759</pubmed>