Spo0B

• Description: sporulation initiation phosphotransferase of the phosphorelay
  
  

Gene name	spo0B
Synonyms	spo0D
Essential	no
Product	sporulation initiation phosphotransferase of the phosphorelay
Function	initiation of sporulation
Gene expression levels in SubtiExpress: spo0B
Interactions involving this protein in SubtInteract: Spo0B
Function and regulation of this protein in SubtiPathways: spo0B
MW, pI	22 kDa, 4.963
Gene length, protein length	576 bp, 192 aa
Immediate neighbours	obg, rpmA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphorelay, phosphoproteins

The gene

Basic information

• Locus tag: BSU27930

Phenotypes of a mutant

Arrest of sporulation at stage 0 (initiation) PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • Spo0B-Spo0F
  • Spo0B-Spo0A
  • YmcA-Spo0F PubMed

• Localization:

Database entries

• Structure: 1F51 (complex with Spo0F), 1IXM

• UniProt: P06535

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spo0B-obg PubMed

• Expression browser: spo0B PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • spo0B12, point mutation 85C>T (=R29W), available in BGSC 1S54
  • spo0B136, amber mutation 103A>T (=K35X), available in BGSC 1S16
  • spo0B580ts, point mutation 193G>A (=E65K), available in BGSC 1S90
  • spo0B581ts, point mutation 461G>A (=G154D), available in BGSC 1S91

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>20413551 12730135,2437099,9141138,3918016,9299348,16788205,12067336,9726997,2118512, 10997904,1846779,9477965, 2537815 23490197</pubmed>