DapF: Difference between revisions
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[cell wall synthesis]]}}, | |||
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | ||
{{SubtiWiki category|[[Biosynthesis of cell wall components]]}}, | |||
{{SubtiWiki category|[[essential genes]]}} | {{SubtiWiki category|[[essential genes]]}} | ||
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=== Additional information=== | === Additional information=== | ||
=The protein= | =The protein= | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
* '''Catalyzed reaction/ biological activity:''' LL- | * '''Catalyzed reaction/ biological activity:''' LL-diaminopimelate --> meso-diaminopimelate | ||
* '''Protein family:''' diaminopimelate epimerase family (according to Swiss-Prot) | * '''Protein family:''' diaminopimelate epimerase family (according to Swiss-Prot) | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
* '''Domains:''' | * '''[[Domains]]:''' | ||
* '''Modification:''' | * '''Modification:''' | ||
* ''' | * '''[[Cofactors]]:''' | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapF_3306040_3306894_-1 dapF] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dapF_3306040_3306894_-1 dapF] {{PubMed|22383849}} | ||
* '''Sigma factor:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 11:48, 5 January 2014
- Description: diaminopimelate epimerase
| Gene name | dapF |
| Synonyms | yutL |
| Essential | yes PubMed |
| Product | diaminopimelate epimerase |
| Function | biosynthesis of lysine and peptidoglycan |
| Gene expression levels in SubtiExpress: dapF | |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 30 kDa, 4.506 |
| Gene length, protein length | 852 bp, 284 aa |
| Immediate neighbours | sufA, yutK |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Categories containing this gene/protein
cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU32170
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: LL-diaminopimelate --> meso-diaminopimelate
- Protein family: diaminopimelate epimerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2OTN (from Bacillus anthracis str. ames, 62% identity, 75% similarity)
- UniProt: O32114
- KEGG entry: [2]
- E.C. number: 5.1.1.7
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody: