Asd: Difference between revisions
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[cell wall synthesis]]}}, | |||
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | {{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}}, | ||
{{SubtiWiki category|[[Biosynthesis of cell wall components]]}}, | |||
{{SubtiWiki category|[[sporulation proteins]]}}, | {{SubtiWiki category|[[sporulation proteins]]}}, | ||
{{SubtiWiki category|[[essential genes]]}}, | {{SubtiWiki category|[[essential genes]]}}, | ||
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=== Additional information=== | === Additional information=== | ||
=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
* '''Domains:''' | * '''[[Domains]]:''' | ||
* '''Modification:''' phosphorylation on Ser-98 AND Tyr-146 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed] | * '''Modification:''' phosphorylation on Ser-98 AND Tyr-146 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed] | ||
* ''' | * '''[[Cofactors]]:''' | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=asd_1745991_1747031_1 asd] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=asd_1745991_1747031_1 asd] {{PubMed|22383849}} | ||
* '''Sigma factor:''' | * '''[[Sigma factor]]:''' | ||
** ''[[spoVFA]]'': [[SigK]] {{PubMed|15699190,8098035}} | ** ''[[spoVFA]]'': [[SigK]] {{PubMed|15699190,8098035}} | ||
** ''[[asd]]'': [[SigA]] {{PubMed|8098035}} | ** ''[[asd]]'': [[SigA]] {{PubMed|8098035}} | ||
Revision as of 11:39, 5 January 2014
- Description: aspartate-semialdehyde dehydrogenase
| Gene name | asd |
| Synonyms | |
| Essential | yes PubMed |
| Product | aspartate-semialdehyde dehydrogenase |
| Function | biosynthesis of threonine, lysine, dipicolic acid, peptidoglycan |
| Gene expression levels in SubtiExpress: asd | |
| Interactions involving this protein in SubtInteract: Asd | |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 37 kDa, 4.971 |
| Gene length, protein length | 1038 bp, 346 aa |
| Immediate neighbours | spoVFB, dapG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Categories containing this gene/protein
cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, sporulation proteins, essential genes, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16750
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH (according to Swiss-Prot)
- Protein family: aspartate-semialdehyde dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification: phosphorylation on Ser-98 AND Tyr-146 PubMed
- Effectors of protein activity:
Database entries
- UniProt: Q04797
- KEGG entry: [3]
- E.C. number: 1.2.1.11
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
<pubmed>8345520,,15699190 8098035,,17218307, </pubmed>