CotS

• Description: outer spore coat protein
  
  

Gene name	cotS
Synonyms
Essential	no
Product	spore coat protein
Function	resistance of the spore
Gene expression levels in SubtiExpress: cotS
MW, pI	40 kDa, 6.641
Gene length, protein length	1053 bp, 351 aa
Immediate neighbours	ytxO, cotSA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon, GerE regulon

The gene

Basic information

• Locus tag: BSU30900

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: cotS family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:
  • outer spore coat, localization depends on CotE PubMed

Database entries

• Structure:

• UniProt: P46914

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotSA-cotS-ytxO PubMed

• Expression browser: cotS PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, GerE) PubMed

• Regulatory mechanism:
  • GerE: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

<pubmed>23202530</pubmed>

Original publications

<pubmed>11737650,7545510,9603889,14702409,10234840,15699190,22171814, 15383836</pubmed>