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RpsR: Difference between revisions

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* '''Kinetic information:'''
* '''Kinetic information:'''


* '''Domains:'''  
* '''[[Domains]]:'''  


* '''Modification:'''
* '''Modification:'''


* '''Cofactor(s):'''
* '''[[Cofactors]]:'''


* '''Effectors of protein activity:'''
* '''Effectors of protein activity:'''


* '''[[SubtInteract|Interactions]]:'''
* '''[[SubtInteract|Interactions]]:'''
** [[RpsF]]-[[RpsR]], the heterodimer binds the structure in the ''[[rpsF]]'' mRNA 5' UTR {{PubMed|24310371}}


* '''[[Localization]]:'''
* '''[[Localization]]:'''
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=Expression and regulation=
=Expression and regulation=
* '''Operon:''' ''[[yyaF]]-[[rpsF]]-[[ssbA]]-[[rpsR]]'' {{PubMed|14762004}}
* '''Operon:'''  
** ''[[yyaF]]-[[rpsF]]-[[ssbA]]-[[rpsR]]'' {{PubMed|14762004}}
** ''[[rpsF]]-[[ssbA]]-[[rpsR]]'' {{PubMed|24310371,22383849}}


* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rpsR_4198603_4198842_-1 rpsR] {{PubMed|22383849}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rpsR_4198603_4198842_-1 rpsR] {{PubMed|22383849}}


* '''[[Sigma factor]]:'''  
* '''[[Sigma factor]]:'''  
** ''[[rpsF]]'': [[SigA]] {{PubMed|24310371}}


* '''Regulation:'''  
* '''Regulation:'''  
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* '''Regulatory mechanism:'''  
* '''Regulatory mechanism:'''  


* '''Additional information:'''  the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
* '''Additional information:'''   
** the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
** the mRNA contains a structured motif in the 5' UTR upstream of the ''[[rpsF]]'' ORF that is bound by [[RpsF]]-[[RpsR]] heterodimers and may be implicated in autogenous regulation {{PubMed|24310371}}
 


=Biological materials =
=Biological materials =
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=References=
=References=
<pubmed>12884008,14762004 ,11948146  19653700 11948165 23002217</pubmed>
<pubmed>12884008,14762004 ,11948146  19653700 11948165 23002217 22383849 24310371 </pubmed>


[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 18:30, 13 December 2013

Gene name rpsR
Synonyms
Essential yes PubMed
Product ribosomal protein S18
Function translation
Gene expression levels in SubtiExpress: rpsR
Interactions involving this protein in SubtInteract: RpsR
MW, pI 8 kDa, 11.494
Gene length, protein length 237 bp, 79 aa
Immediate neighbours exoA, ssbA
Sequences Protein DNA DNA_with_flanks
Genetic context
This image was kindly provided by SubtiList
Expression at a glance   PubMed















Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

ComK regulon, stringent response

The gene

Basic information

  • Locus tag: BSU40890

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
    • ComK: transcription activation PubMed
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is very stable (half-life > 15 min) PubMed
    • the mRNA contains a structured motif in the 5' UTR upstream of the rpsF ORF that is bound by RpsF-RpsR heterodimers and may be implicated in autogenous regulation PubMed


Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>12884008,14762004 ,11948146 19653700 11948165 23002217 22383849 24310371 </pubmed>