CapB: Difference between revisions
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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=== Additional information=== | === Additional information=== | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
* '''Domains:''' | * '''[[Domains]]:''' | ||
* '''Modification:''' | * '''Modification:''' | ||
* ''' | * '''[[Cofactors]]:''' | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
* '''Regulatory mechanism:''' [[DegU]]-P: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/19734658 PubMed] | * '''Regulatory mechanism:''' | ||
** [[DegU]]-P: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/19734658 PubMed] | |||
* '''Additional information:''' The operon is not expressed in the lab strain 168 due to lack of expression of [[DegQ]] resulting in inactivity of [[DegS]] and [[DegU]] {{PubMed|21965392}} | * '''Additional information:''' | ||
** The operon is not expressed in the lab strain 168 due to lack of expression of [[DegQ]] resulting in inactivity of [[DegS]] and [[DegU]] {{PubMed|21965392}} | |||
** expression of the operon is reduced in ''[[motA]]'' or ''[[motB]]'' mutants due to reduced [[DegU]] phosphorylation {{PubMed|24296669}} | |||
=Biological materials = | =Biological materials = | ||
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<pubmed>20735481 </pubmed> | <pubmed>20735481 </pubmed> | ||
==Original publications== | ==Original publications== | ||
<pubmed>11751809,19420703, 19389763, 16233197 19734658 20564357 20564574 24296669 21965392</pubmed> | |||
<pubmed>11751809,19420703, 19389763, 16233197 19734658 20564357 20564574 </pubmed> | |||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:12, 4 December 2013
- Description: capsular polyglutamate biosynthesis
| Gene name | capB |
| Synonyms | ywsC, pgsB |
| Essential | no |
| Product | poly-gamma-glutamate synthetase |
| Function | capsule synthesis |
| Gene expression levels in SubtiExpress: capB | |
| MW, pI | 43 kDa, 5.073 |
| Gene length, protein length | 1179 bp, 393 aa |
| Immediate neighbours | capC, rbsR |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Categories containing this gene/protein
capsule biosynthesis and degradation
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35900
Phenotypes of a mutant
no synthesis of the poly-gamma-glutamate capsule PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: synthesis of poly-gamma-glutamate from L-Glu PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P96736
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
<pubmed>20735481 </pubmed>
Original publications
<pubmed>11751809,19420703, 19389763, 16233197 19734658 20564357 20564574 24296669 21965392</pubmed>