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RnpB: Difference between revisions

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|style="background:#ABCDEF;" align="center"|'''Function''' || cleavage of precursor sequences <br/>from the 5' ends of pre-tRNAs
|style="background:#ABCDEF;" align="center"|'''Function''' || cleavage of precursor sequences <br/>from the 5' ends of pre-tRNAs
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this RNA in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RnpB RnpB]
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this RNA in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RnpB RnpB]
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|style="background:#ABCDEF;" align="center"| '''Gene length''' ||  401 bp
|style="background:#ABCDEF;" align="center"| '''Gene length''' ||  401 bp

Revision as of 08:41, 12 November 2013

  • Description: RNA component of RNase P

Gene name rnpB
Synonyms rnaP
Essential yes PubMed
Product RNA component of ribonuclease P
(RNase P) (catalytic subunit, ribozyme)
Function cleavage of precursor sequences
from the 5' ends of pre-tRNAs
Interactions involving this RNA in SubtInteract: RnpB
Gene length 401 bp
Immediate neighbours ypsC, ypsB
Gene sequence (+200bp)
Genetic context
This image was kindly provided by SubtiList








Categories containing this gene/protein

Rnases, translation, ncRNA, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]
  • Structure:
    • 2A64 (from Geobacillus stearothermophilus)
    • 1NBS (specificity domain)
    • 3OKB (complex of RnpA with the RNA RnpB and tRNA, from Thermotoga maritima) PubMed

The RNA

  • Biological activity: 5' end maturation of precursor tRNAs
  • RNA family:
  • cofactor: divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA PubMed

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/RNA

Your additional remarks

References

Reviews

<pubmed> 19215776 17868095 14691942 16650980 16980936 16679018 14550630 </pubmed>

Original Publications

Additional publications: PubMed <pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747 19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed>