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| * '''Description:''' monooxygenase, required for the conversion of S-methyl-cysteine to cysteine <br/><br/>
| | {{#bank: CmoO}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''cmoO''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ytmO ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || monooxygenase
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| |style="background:#ABCDEF;" align="center"|'''Function''' || utilization of S-methyl-cysteine
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| |-
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29330 cmoO]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/riboflavin.html Riboflavin / FAD]'''
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 5.845
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1002 bp, 334 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cmoI]]'', ''[[tcyN]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29330 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29330 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29330 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:ytmO_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytmO_3003345_3004349_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:ytmO_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29330]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[sulfur metabolism]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[CymR regulon]]}},
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| {{SubtiWiki regulon|[[AscR regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU29330
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| ===Phenotypes of a mutant ===
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| * no growth with S-methyl cysteine {{PubMed|23944997}}
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ytmIJKLMNO-ytnIJ-ribR-ytnLM.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13888]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O34846 O34846]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU29330]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[snaA]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[cmoO]]-[[cmoI]]-[[cmoJ]]-[[ribR]]-[[sndA]]-[[ytnM]]'' {{PubMed|15668000}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytmO_3003345_3004349_-1 cmoO] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15272571}}
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| * '''Regulation:'''
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| ** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
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| ** induced in the presence of S-methyl-cysteine ([[AscR]]) {{PubMed|23944997}}
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| * '''Regulatory mechanism:'''
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| ** [[CymR]]: transcription repression {{PubMed|16109943}}
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| ** [[AscR]]: transcription activation {{PubMed|16109943}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>16109943,15668000, 15272571 23944997</pubmed>
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| [[Category:Protein-coding genes]]
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